@Article{info:doi/10.2196/41012, author="Dub{\'e}, Eve and MacDonald, Shannon E and Manca, Terra and Bettinger, Julie A and Driedger, S Michelle and Graham, Janice and Greyson, Devon and MacDonald, Noni E and Meyer, Samantha and Roch, Genevi{\`e}ve and Vivion, Maryline and Aylsworth, Laura and Witteman, Holly O and G{\'e}linas-Gascon, F{\'e}lix and Marques Sathler Guimaraes, Lucas and Hakim, Hina and Gagnon, Dominique and B{\'e}chard, Beno{\^i}t and Gramaccia, Julie A and Khoury, Richard and Tremblay, S{\'e}bastien", title="Understanding the Influence of Web-Based Information, Misinformation, Disinformation, and Reinformation on COVID-19 Vaccine Acceptance: Protocol for a Multicomponent Study", journal="JMIR Res Protoc", year="2022", month="Oct", day="17", volume="11", number="10", pages="e41012", keywords="vaccine hesitancy; COVID-19; misinformation; vaccine decisions; disinformation; online; vaccine; vaccination", abstract="Background: The COVID-19 pandemic has generated an explosion in the amount of information shared on the internet, including false and misleading information on SARS-CoV-2 and recommended protective behaviors. Prior to the pandemic, web-based misinformation and disinformation were already identified as having an impact on people's decision to refuse or delay recommended vaccination for themselves or their children. Objective: The overall aims of our study are to better understand the influence of web-based misinformation and disinformation on COVID-19 vaccine decisions and investigate potential solutions to reduce the impact of web-based misinformation and disinformation about vaccines. Methods: Based on different research approaches, the study will involve (1) the use of artificial intelligence techniques, (2) a web-based survey, (3) interviews, and (4) a scoping review and an environmental scan of the literature. Results: As of September 1, 2022, data collection has been completed for all objectives. The analysis is being conducted, and results should be disseminated in the upcoming months. Conclusions: The findings from this study will help with understanding the underlying determinants of vaccine hesitancy among Canadian individuals and identifying effective, tailored interventions to improve vaccine acceptance among them. International Registered Report Identifier (IRRID): DERR1-10.2196/41012 ", issn="1929-0748", doi="10.2196/41012", url="https://www.researchprotocols.org/2022/10/e41012", url="https://doi.org/10.2196/41012", url="http://www.ncbi.nlm.nih.gov/pubmed/36191171" }