@Article{info:doi/10.2196/36294, author="Grecco, Leandro H and Gon{\c{c}}alves, Giuliano R and Perri, B{\'a}rbara Neiva and Bispo, Breno Alexander and Grandin, Isabella Favilla Jorge and Gomes, Paula Valentina Nunes Dias and Bocchi, Andr{\'e} Alexandre and Oliveira, Kennedy Martinez and Maldonado, Diogo Correa and Silva, Marcelo Cavenaghi Pereira da", title="Association of Transcranial Direct Current Stimulation and Neurofeedback With Declarative Memory and Cerebral Arterial Flow in University Students: Protocol for a Double-blind Randomized Controlled Study", journal="JMIR Res Protoc", year="2022", month="Aug", day="26", volume="11", number="8", pages="e36294", keywords="transcranial direct current stimulation; neurofeedback stimulation; TDCS; memory; Doppler ultrasonography; arterial flow; brain stimulation; electrical stimulation; transcranial; neurofeedback; brain; neurology; cerebral; blood flow; cerebrum; declarative memory; double-blind; controlled trial; RCT; randomized controlled trial; university; college; student; postsecondary; graduate; undergraduate", abstract="Background: The performance of a task depends on ongoing brain activity, which can be influenced by attention, excitement, or motivation. Scientific studies have confirmed that mindfulness leads to better performance, health, and well-being. However, these cognitive efficiency modulating factors are nonspecific, can be difficult to control, and are not suitable to specifically facilitate neural processing. Objective: The aim of this study is to evaluate the effects of transcranial direct current stimulation associated with neurofeedback on declarative memory and cerebral blood flow in university students. Methods: In this study, we will use transcranial direct current stimulation, a low-cost physical resource that is easy to apply, has few adverse effects, and is associated with a neurofeedback resource. This, in turn, has been shown to be a training program capable of improving working memory function. Results: Participants will be recruited between July 2022 and December 2022. This study is expected to conclude in July 2023. Conclusions: This study will provide preliminary results on the benefits of using the direct current neurostimulation and neurofeedback tools on the participants being analyzed. Trial Registration: Brazilian Clinical Trials Registry RBR-7zs8b5; https://ensaiosclinicos.gov.br/rg/RBR-7zs8b5 International Registered Report Identifier (IRRID): PRR1-10.2196/36294 ", issn="1929-0748", doi="10.2196/36294", url="https://www.researchprotocols.org/2022/8/e36294", url="https://doi.org/10.2196/36294", url="http://www.ncbi.nlm.nih.gov/pubmed/36018619" }