%0 Journal Article
%@ 1929-0748
%I JMIR Publications
%V 11
%N 3
%P e32163
%T Rehabilitation Using Mobile Health for Older Adults With Ischemic Heart Disease in the Home Setting (RESILIENT): Protocol for a Randomized Controlled Trial
%A Dodson,John A
%A Schoenthaler,Antoinette
%A Sweeney,Greg
%A Fonceva,Ana
%A Pierre,Alicia
%A Whiteson,Jonathan
%A George,Barbara
%A Marzo,Kevin
%A Drewes,Wendy
%A Rerisi,Elizabeth
%A Mathew,Reena
%A Aljayyousi,Haneen
%A Chaudhry,Sarwat I
%A Hajduk,Alexandra M
%A Gill,Thomas M
%A Estrin,Deborah
%A Kovell,Lara
%A Jennings,Lee A
%A Adhikari,Samrachana
%+ Geriatric Cardiology Program, Medicine and Population Health, Leon H Charney Division of Cardiology, NYU Grossman School of Medicine, Translational Research Building, 227 East 30th Street, New York, NY, 10016, United States, 1 646 501 2714, john.dodson@nyulangone.org
%K mobile health
%K cardiac rehabilitation
%K clinical trial
%K rehabilitation
%K cardiology
%K heart disease
%K ambulatory care
%K mHealth
%K health outcomes
%K older adults
%D 2022
%7 3.3.2022
%9 Protocol
%J JMIR Res Protoc
%G English
%X Background: Participation in ambulatory cardiac rehabilitation remains low, especially among older adults. Although mobile health cardiac rehabilitation (mHealth-CR) provides a novel opportunity to deliver care, age-specific impairments may limit older adults’ uptake, and efficacy data are currently lacking. Objective: This study aims to describe the design of the rehabilitation using mobile health for older adults with ischemic heart disease in the home setting (RESILIENT) trial. Methods: RESILIENT is a multicenter randomized clinical trial that is enrolling patients aged ≥65 years with ischemic heart disease in a 3:1 ratio to either an intervention (mHealth-CR) or control (usual care) arm, with a target sample size of 400 participants. mHealth-CR consists of a commercially available mobile health software platform coupled with weekly exercise therapist sessions to review progress and set new activity goals. The primary outcome is a change in functional mobility (6-minute walk distance), which is measured at baseline and 3 months. Secondary outcomes are health status, goal attainment, hospital readmission, and mortality. Among intervention participants, engagement with the mHealth-CR platform will be analyzed to understand the characteristics that determine different patterns of use (eg, persistent high engagement and declining engagement). Results: As of December 2021, the RESILIENT trial had enrolled 116 participants. Enrollment is projected to continue until October 2023. The trial results are expected to be reported in 2024. Conclusions: The RESILIENT trial will generate important evidence about the efficacy of mHealth-CR among older adults in multiple domains and characteristics that determine the sustained use of mHealth-CR. These findings will help design future precision medicine approaches to mobile health implementation in older adults. This knowledge is especially important in light of the COVID-19 pandemic that has shifted much of health care to a remote, internet-based setting. Trial Registration: ClinicalTrials.gov NCT03978130; https://clinicaltrials.gov/ct2/show/NCT03978130 International Registered Report Identifier (IRRID): DERR1-10.2196/32163 
%M 35238793
%R 10.2196/32163
%U https://www.researchprotocols.org/2022/3/e32163
%U https://doi.org/10.2196/32163
%U http://www.ncbi.nlm.nih.gov/pubmed/35238793