%0 Journal Article %@ 1929-0748 %I JMIR Publications %V 11 %N 6 %P e12506 %T Biomedical Research and Informatics Living Laboratory for Innovative Advances of New Technologies in Community Mobility Rehabilitation: Protocol for Evaluation and Rehabilitation of Mobility Across Continuums of Care %A Ahmed,Sara %A Archambault,Philippe %A Auger,Claudine %A Durand,Audrey %A Fung,Joyce %A Kehayia,Eva %A Lamontagne,Anouk %A Majnemer,Annette %A Nadeau,Sylvie %A Pineau,Joelle %A Ptito,Alain %A Swaine,Bonnie %+ School of Physical and Occupational Therapy, Faculty of Medicine and Health Sciences, McGill University, 3654 Prom Sir-William-Osler, Montreal, QC, H3G 1Y5, Canada, 1 514 802 1366, sara.ahmed@mcgill.ca %K health informatics %K digital health %K individualized care %K acquired brain injury %K community mobility %K participation %K physical rehabilitation %K virtual reality %K artificial intelligence %K predictive analytics %K biomedical %K learning health system %D 2022 %7 1.6.2022 %9 Protocol %J JMIR Res Protoc %G English %X Background: Rapid advances in technologies over the past 10 years have enabled large-scale biomedical and psychosocial rehabilitation research to improve the function and social integration of persons with physical impairments across the lifespan. The Biomedical Research and Informatics Living Laboratory for Innovative Advances of New Technologies (BRILLIANT) in community mobility rehabilitation aims to generate evidence-based research to improve rehabilitation for individuals with acquired brain injury (ABI). Objective: This study aims to (1) identify the factors limiting or enhancing mobility in real-world community environments (public spaces, including the mall, home, and outdoors) and understand their complex interplay in individuals of all ages with ABI and (2) customize community environment mobility training by identifying, on a continuous basis, the specific rehabilitation strategies and interventions that patient subgroups benefit from most. Here, we present the research and technology plan for the BRILLIANT initiative. Methods: A cohort of individuals, adults and children, with ABI (N=1500) will be recruited. Patients will be recruited from the acute care and rehabilitation partner centers within 4 health regions (living labs) and followed throughout the continuum of rehabilitation. Participants will also be recruited from the community. Biomedical, clinician-reported, patient-reported, and brain imaging data will be collected. Theme 1 will implement and evaluate the feasibility of collecting data across BRILLIANT living labs and conduct predictive analyses and artificial intelligence (AI) to identify mobility subgroups. Theme 2 will implement, evaluate, and identify community mobility interventions that optimize outcomes for mobility subgroups of patients with ABI. Results: The biomedical infrastructure and equipment have been established across the living labs, and development of the clinician- and patient-reported outcome digital solutions is underway. Recruitment is expected to begin in May 2022. Conclusions: The program will develop and deploy a comprehensive clinical and community-based mobility-monitoring system to evaluate the factors that result in poor mobility, and develop personalized mobility interventions that are optimized for specific patient subgroups. Technology solutions will be designed to support clinicians and patients to deliver cost-effective care and the right intervention to the right person at the right time to optimize long-term functional potential and meaningful participation in the community. International Registered Report Identifier (IRRID): PRR1-10.2196/12506 %M 35648455 %R 10.2196/12506 %U https://www.researchprotocols.org/2022/6/e12506 %U https://doi.org/10.2196/12506 %U http://www.ncbi.nlm.nih.gov/pubmed/35648455