%0 Journal Article
%@ 1929-0748
%I JMIR Publications
%V 11
%N 8
%P e36294
%T Association of Transcranial Direct Current Stimulation and Neurofeedback With Declarative Memory and Cerebral Arterial Flow in University Students: Protocol for a Double-blind Randomized Controlled Study
%A Grecco,Leandro H
%A Gonçalves,Giuliano R
%A Perri,Bárbara Neiva
%A Bispo,Breno Alexander
%A Grandin,Isabella Favilla Jorge
%A Gomes,Paula Valentina Nunes Dias
%A Bocchi,André Alexandre
%A Oliveira,Kennedy Martinez
%A Maldonado,Diogo Correa
%A Silva,Marcelo Cavenaghi Pereira da
%+ Department of Morphology and Genetics, Universidade Federal de São Paulo, Rua Botucatu, 682, São Paulo, 04021-001, Brazil, 55 11 5576 4848, leandrohgrecco@gmail.com
%K transcranial direct current stimulation
%K neurofeedback stimulation
%K TDCS
%K memory
%K Doppler ultrasonography
%K arterial flow
%K brain stimulation
%K electrical stimulation
%K transcranial
%K neurofeedback
%K brain
%K neurology
%K cerebral
%K blood flow
%K cerebrum
%K declarative memory
%K double-blind
%K controlled trial
%K RCT
%K randomized controlled trial
%K university
%K college
%K student
%K postsecondary
%K graduate
%K undergraduate
%D 2022
%7 26.8.2022
%9 Protocol
%J JMIR Res Protoc
%G English
%X Background: The performance of a task depends on ongoing brain activity, which can be influenced by attention, excitement, or motivation. Scientific studies have confirmed that mindfulness leads to better performance, health, and well-being. However, these cognitive efficiency modulating factors are nonspecific, can be difficult to control, and are not suitable to specifically facilitate neural processing. Objective: The aim of this study is to evaluate the effects of transcranial direct current stimulation associated with neurofeedback on declarative memory and cerebral blood flow in university students. Methods: In this study, we will use transcranial direct current stimulation, a low-cost physical resource that is easy to apply, has few adverse effects, and is associated with a neurofeedback resource. This, in turn, has been shown to be a training program capable of improving working memory function. Results: Participants will be recruited between July 2022 and December 2022. This study is expected to conclude in July 2023. Conclusions: This study will provide preliminary results on the benefits of using the direct current neurostimulation and neurofeedback tools on the participants being analyzed. Trial Registration: Brazilian Clinical Trials Registry RBR-7zs8b5; https://ensaiosclinicos.gov.br/rg/RBR-7zs8b5 International Registered Report Identifier (IRRID): PRR1-10.2196/36294 
%M 36018619
%R 10.2196/36294
%U https://www.researchprotocols.org/2022/8/e36294
%U https://doi.org/10.2196/36294
%U http://www.ncbi.nlm.nih.gov/pubmed/36018619