TY  - JOUR
AU  - Smith, Isabelle S
AU  - Wallace, Rebecca
AU  - Wellecke, Cornelia
AU  - Bind, Marie-Abèle
AU  - Weihs, Karen L
AU  - Bei, Bei
AU  - Wiley, Joshua F
PY  - 2022
DA  - 2022/7/27
TI  - Assessing an Internet-Delivered, Emotion-Focused Intervention Compared With a Healthy Lifestyle Active Control Intervention in Improving Mental Health in Cancer Survivors: Protocol for a Randomized Controlled Trial
JO  - JMIR Res Protoc
SP  - e36658
VL  - 11
IS  - 7
KW  - cancer survivor
KW  - depressive symptoms
KW  - anxiety symptoms
KW  - emotion regulation
KW  - Unified Protocol
KW  - transdiagnostic
KW  - internet-delivered intervention
KW  - quality of life
KW  - eHealth
KW  - randomized controlled trial
KW  - psycho-oncology
KW  - mobile phone
AB  - Background: Cancer survivors are vulnerable to experiencing symptoms of anxiety and depression and may benefit from accessible interventions focused on improving emotion regulation. CanCope Mind (CM) was developed as an internet-delivered intervention adapted from the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders to improve emotion regulation and support the mental health of cancer survivors. Objective: This protocol aims to provide an outline of the CanCope Study, a trial comparing the efficacy of a Unified Protocol–adapted internet-delivered intervention (CM) designed for cancer survivors compared with an active control condition—an internet-delivered healthy lifestyle intervention, CanCope Lifestyle (CL). The primary aim is to assess and compare the efficacy of both interventions in improving emotion regulation, anxiety and depressive symptoms, and quality of life. The secondary aims involve assessing the mechanisms of the CM intervention. Methods: This trial is a 2-arm randomized controlled trial that allocates cancer survivors to either CM or CL. Both interventions comprise 4 web-based modules and are expected to take participants at least 8 weeks to complete. Participants’ mental and physical health will be assessed via self-reported surveys at baseline (T0), between each module (T1, T2, and T3), immediately after the intervention (T4), and at 3-month follow-up (T5). The study aims to recruit 110 participants who have completed T4. Results: The CanCope study began recruitment in September 2020. A total of 224 participants have been randomized to the CM (n=110, 49.1%) and CL (n=114, 50.9%) groups. Conclusions: This is one of the first trials to develop and investigate the efficacy of a web-based intervention for cancer survivors that specifically targets emotion regulation. Trial Registration: Australian Clinical Trials ACTRN12620000943943; https://tinyurl.com/b3z9cjsp International Registered Report Identifier (IRRID): DERR1-10.2196/36658 
SN  - 1929-0748
UR  - https://www.researchprotocols.org/2022/7/e36658
UR  - https://doi.org/10.2196/36658
UR  - http://www.ncbi.nlm.nih.gov/pubmed/35896021
DO  - 10.2196/36658
ID  - info:doi/10.2196/36658
ER  -