TY  - JOUR
AU  - Hammami, Rania
AU  - Boudiche, Selim
AU  - Rami, Tlili
AU  - Ben Halima, Nejeh
AU  - Jamel, Ahmed
AU  - Rekik, Bassem
AU  - Gribaa, Rym
AU  - Imtinene, Ben Mrad
AU  - Charfeddine, Salma
AU  - Ellouze, Tarek
AU  - Bahloul, Amine
AU  - Hédi, Ben Slima
AU  - Langar, Jamel
AU  - Ben Ahmed, Habib
AU  - Ibn Elhadj, Zied
AU  - Hmam, Mohamed
AU  - Ben Abdessalem, Mohamed Aymen
AU  - Maaoui, Sabri
AU  - Fennira, Sana
AU  - Lobna, Laroussi
AU  - Hassine, Majed
AU  - Ouanes, Sami
AU  - Mohamed Faouzi, Drissi
AU  - Mallek, Souad
AU  - Mahdhaoui, Abdallah
AU  - Meriem, Dghim
AU  - Jomaa, Walid
AU  - Zayed, Sofien
AU  - Kateb, Tawfik
AU  - Bouchahda, Nidhal
AU  - Azaiez, Fares
AU  - Ben Salem, Helmi
AU  - Marouen, Morched
AU  - Noamen, Aymen
AU  - Abdesselem, Salem
AU  - Hichem, Denguir
AU  - Ibn Hadj Amor, Hassen
AU  - Abdeljelil, Farhati
AU  - Amara, Amine
AU  - Bejar, Karim
AU  - Khaldoun, Ben Hamda
AU  - Hamza, Chiheb
AU  - Ben Jamaa, Mohsen
AU  - Fourati, Sami
AU  - Elleuch, Faycal
AU  - Grati, Zeineb
AU  - Chtourou, Slim
AU  - Marouene, Sami
AU  - Sahnoun, Mohamed
AU  - Hadrich, Morched
AU  - Mohamed Abdelkader, Maalej
AU  - Bouraoui, Hatem
AU  - Kamoun, Kamel
AU  - Hadrich, Moufid
AU  - Ben Chedli, Tarek
AU  - Drissa, Mohamed Akrem
AU  - Charfeddine, Hanene
AU  - Saadaoui, Nizar
AU  - Achraf, Gargouri
AU  - Ahmed, Siala
AU  - Ayari, Mokdad
AU  - Nabil, Marsit
AU  - Mnif, Sabeur
AU  - Sahnoun, Maher
AU  - Kammoun, Helmi
AU  - Ben Jemaa, Khaled
AU  - Mostari, Gharbi
AU  - Hamrouni, Nebil
AU  - Yamen, Maazoun
AU  - Ellouz, Yassine
AU  - Smiri, Zahreddine
AU  - Hdiji, Amine
AU  - Bassem, Jerbi
AU  - Ayadi, Wacef
AU  - Zouari, Amir
AU  - Abbassi, Chedly
AU  - Fatma, Boujelben Masmoudi
AU  - Battikh, Kais
AU  - Kharrat, Elyes
AU  - Gtif, Imen
AU  - Sami, Milouchi
AU  - Bezdah, Leila
AU  - Kachboura, Salem
AU  - Maatouk, Mohamed Faouzi
AU  - Kraiem, Sondes
AU  - Jeridi, Gouider
AU  - Neffati, Elyes
AU  - Kammoun, Samir
AU  - Ben Ameur, Youssef
AU  - Fehri, Wafa
AU  - Gamra, Habib
AU  - Zakhama, Lilia
AU  - Addad, Faouzi
AU  - Mohamed Sami, Mourali
AU  - Abid, Leila
PY  - 2022
DA  - 2022/8/5
TI  - Design and Rationale of the National Tunisian Registry of Percutaneous Coronary Intervention: Protocol for a Prospective Multicenter Observational Study
JO  - JMIR Res Protoc
SP  - e24595
VL  - 11
IS  - 8
KW  - percutaneous coronary intervention
KW  - 1-year outcome
KW  - Tunisia
KW  - national
KW  - multicentric
KW  - registry
KW  - percutaneous
KW  - coronary
KW  - artery disease
AB  - Background: Coronary artery diseases remain the leading cause of death in the world. The management of this condition has improved remarkably in the recent years owing to the development of new technical tools and multicentric registries. Objective: The aim of this study is to investigate the in-hospital and 1-year clinical outcomes of patients treated with percutaneous coronary intervention (PCI) in Tunisia. Methods: We will conduct a prospective multicentric observational study with patients older than 18 years who underwent PCI between January 31, 2020 and June 30, 2020. The primary end point is the occurrence of a major adverse cardiovascular event, defined as cardiovascular death, myocardial infarction, cerebrovascular accident, or target vessel revascularization with either repeat PCI or coronary artery bypass grafting (CABG). The secondary end points are procedural success rate, stent thrombosis, and the rate of redo PCI/CABG for in-stent restenosis. Results: In this study, the demographic profile and the general risk profile of Tunisian patients who underwent PCI and their end points will be analyzed. The complexity level of the procedures and the left main occlusion, bifurcation occlusion, and chronic total occlusion PCI will be analyzed, and immediate as well as long-term results will be determined. The National Tunisian Registry of PCI (NATURE-PCI) will be the first national multicentric registry of angioplasty in Africa. For this study, the institutional ethical committee approval was obtained (0223/2020). This trial consists of 97 cardiologists and 2498 patients who have undergone PCI with a 1-year follow-up period. Twenty-eight catheterization laboratories from both public (15 laboratories) and private (13 laboratories) sectors will enroll patients after receiving informed consent. Of the 2498 patients, 1897 (75.9%) are managed in the public sector and 601 (24.1%) are managed in the private sector. The COVID-19 pandemic started in Tunisia in March 2020; 719 patients (31.9%) were included before the COVID-19 pandemic and 1779 (60.1%) during the pandemic. The inclusion of patients has been finished, and we expect to publish the results by the end of 2022. Conclusions: This study would add data and provide a valuable opportunity for real-world clinical epidemiology and practice in the field of interventional cardiology in Tunisia with insights into the uptake of PCI in this limited-income region. Trial Registration: Clinicaltrials.gov NCT04219761; https://clinicaltrials.gov/ct2/show/NCT04219761 International Registered Report Identifier (IRRID): RR1-10.2196/24595 
SN  - 1929-0748
UR  - https://www.researchprotocols.org/2022/8/e24595
UR  - https://doi.org/10.2196/24595
UR  - http://www.ncbi.nlm.nih.gov/pubmed/35930353
DO  - 10.2196/24595
ID  - info:doi/10.2196/24595
ER  -