TY  - JOUR
AU  - Grecco, Leandro H
AU  - Gonçalves, Giuliano R
AU  - Perri, Bárbara Neiva
AU  - Bispo, Breno Alexander
AU  - Grandin, Isabella Favilla Jorge
AU  - Gomes, Paula Valentina Nunes Dias
AU  - Bocchi, André Alexandre
AU  - Oliveira, Kennedy Martinez
AU  - Maldonado, Diogo Correa
AU  - Silva, Marcelo Cavenaghi Pereira da
PY  - 2022
DA  - 2022/8/26
TI  - Association of Transcranial Direct Current Stimulation and Neurofeedback With Declarative Memory and Cerebral Arterial Flow in University Students: Protocol for a Double-blind Randomized Controlled Study
JO  - JMIR Res Protoc
SP  - e36294
VL  - 11
IS  - 8
KW  - transcranial direct current stimulation
KW  - neurofeedback stimulation
KW  - TDCS
KW  - memory
KW  - Doppler ultrasonography
KW  - arterial flow
KW  - brain stimulation
KW  - electrical stimulation
KW  - transcranial
KW  - neurofeedback
KW  - brain
KW  - neurology
KW  - cerebral
KW  - blood flow
KW  - cerebrum
KW  - declarative memory
KW  - double-blind
KW  - controlled trial
KW  - RCT
KW  - randomized controlled trial
KW  - university
KW  - college
KW  - student
KW  - postsecondary
KW  - graduate
KW  - undergraduate
AB  - Background: The performance of a task depends on ongoing brain activity, which can be influenced by attention, excitement, or motivation. Scientific studies have confirmed that mindfulness leads to better performance, health, and well-being. However, these cognitive efficiency modulating factors are nonspecific, can be difficult to control, and are not suitable to specifically facilitate neural processing. Objective: The aim of this study is to evaluate the effects of transcranial direct current stimulation associated with neurofeedback on declarative memory and cerebral blood flow in university students. Methods: In this study, we will use transcranial direct current stimulation, a low-cost physical resource that is easy to apply, has few adverse effects, and is associated with a neurofeedback resource. This, in turn, has been shown to be a training program capable of improving working memory function. Results: Participants will be recruited between July 2022 and December 2022. This study is expected to conclude in July 2023. Conclusions: This study will provide preliminary results on the benefits of using the direct current neurostimulation and neurofeedback tools on the participants being analyzed. Trial Registration: Brazilian Clinical Trials Registry RBR-7zs8b5; https://ensaiosclinicos.gov.br/rg/RBR-7zs8b5 International Registered Report Identifier (IRRID): PRR1-10.2196/36294 
SN  - 1929-0748
UR  - https://www.researchprotocols.org/2022/8/e36294
UR  - https://doi.org/10.2196/36294
UR  - http://www.ncbi.nlm.nih.gov/pubmed/36018619
DO  - 10.2196/36294
ID  - info:doi/10.2196/36294
ER  -