TY  - JOUR
AU  - Seid, Abubeker Alebachew
AU  - Moloro, Abdulkerim Hassen
PY  - 2022
DA  - 2022/9/7
TI  - Effectiveness of Neurodynamic Interventions in Patients With Stroke: Protocol for a Systematic Review and Meta-analysis
JO  - JMIR Res Protoc
SP  - e38956
VL  - 11
IS  - 9
KW  - stroke
KW  - neurodynamic
KW  - neurological
KW  - physiotherapy
KW  - physiotherapist
KW  - neural mobilization
KW  - review
KW  - intervention
KW  - search strategy
KW  - search strategies
KW  - library science
KW  - information science
KW  - librarian
KW  - pain
KW  - quality of life
KW  - disability
KW  - disabilities
KW  - physical function
AB  - Background: Stroke is the most common and serious neurological condition, which can lead to death, limited functionality, and reduced quality of life. Studies with conflicting results and various methodological limitations have been conducted to assess the effectiveness of neurodynamic interventions for patients with stroke. Objective: This systematic review and meta-analysis aimed to investigate the pooled effectiveness of different neurodynamic interventions on patients with stroke. Methods: The PubMed, PEDro, and Google Scholar databases will be searched for studies published with full text in the English language from inception to date. Randomized controlled trials evaluating the effect of different neurodynamic techniques on patients with stroke will be included. The primary outcome measures will include pain, disability/function, and quality of life. Secondary outcome measures will include physical performance measures such as balance, range of motion, muscle strength, and specific diagnostic and neurodynamic test outcomes. The screening, data extraction, and methodological quality assessment will be performed by two independent reviewers. The PEDro scale will be used to systematically appraise the methodological quality. Review Manager V.5.4 software will be used for statistical analysis. Weighted mean difference or standardized mean difference with 95% CIs and P values will be used to calculate the treatment effect for each outcome variable. Results: Search terms and search databases have been identified. The data extraction sheet has also been developed. This study is expected to be completed by the end of 2022. Conclusions: This study will provide up-to-date evidence on the effectiveness and use of neurodynamic interventions for patients with stroke in clinical practice. Trial Registration: PROSPERO CRD42022319972; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=319972 International Registered Report Identifier (IRRID): PRR1-10.2196/38956 
SN  - 1929-0748
UR  - https://www.researchprotocols.org/2022/9/e38956
UR  - https://doi.org/10.2196/38956
UR  - http://www.ncbi.nlm.nih.gov/pubmed/36069824
DO  - 10.2196/38956
ID  - info:doi/10.2196/38956
ER  -