TY  - JOUR
AU  - Kromer, Christian
AU  - Nühnen, Viktoria P
AU  - Pfützner, Wolfgang
AU  - Pfeiffer, Sebastian
AU  - Laubach, Hans-Joachim
AU  - Boehncke, Wolf-Henning
AU  - Liebmann, Joerg
AU  - Born, Matthias
AU  - Schön, Michael P
AU  - Buhl, Timo
PY  - 2019
DA  - 2019/01/08
TI  - Treatment of Atopic Dermatitis Using a Full-Body Blue Light Device (AD-Blue): Protocol of a Randomized Controlled Trial
JO  - JMIR Res Protoc
SP  - e11911
VL  - 8
IS  - 1
KW  - atopic dermatitis
KW  - atopic eczema
KW  - blue light
KW  - irradiation
KW  - ultraviolet light
AB  - Background: Irradiation with visible blue light (wavelength 400-495 nm) is a promising, effective, and safe new treatment option for chronic inflammatory skin diseases such as psoriasis and atopic dermatitis. Objective: We will perform a multicenter, placebo-controlled, double-blinded, 3-armed, prospective, randomized controlled trial to investigate the efficacy and safety of full-body blue light devices (wavelengths: 415 nm and 450 nm) compared with that of placebo irradiation for the treatment of atopic dermatitis. Methods: We are planning to enroll a total of 150 patients at the University hospitals in Göttingen (Germany), Marburg (Germany), and Geneva (Switzerland). Results: The trial was approved by the lead ethics committee of the medical faculty of the University of Göttingen (21/11/16). Further approvals were obtained from local and federal authorities (ethics committee Marburg, Cantonal Commission for Research Ethics Geneva, Suisse Medic, and Bundesinstitut für Arzneimittel und Medizinprodukte). Conclusions: We will disseminate the results in a peer-reviewed journal. Trial Registration: ClinicalTrials.gov NCT03085303; https://clinicaltrials.gov/ct2/show/NCT03085303 (Archived by WebCite at http://www.webcitation.org/73ucqkkA1) International Registered Report Identifier (IRRID): DERR1-10.2196/11911 
SN  - 1929-0748
UR  - http://www.researchprotocols.org/2019/1/e11911/
UR  - https://doi.org/10.2196/11911
UR  - http://www.ncbi.nlm.nih.gov/pubmed/30622089
DO  - 10.2196/11911
ID  - info:doi/10.2196/11911
ER  -