JMIR Research Protocols

Protocols, grant proposals, registered reports (RR1)

Editor-in-Chief:

Amy Schwartz, MSc, Ph.D., Scientific Editor at JMIR Publications, Ontario, Canada


Impact Factor 1.4 CiteScore 2.4

JMIR Research Protocols  (JRP, ISSN 1929-0748) is a unique journal indexed in PubMed, PubMed Central (PMC), MEDLINE, Sherpa Romeo, DOAJ, Scopus, Web of Science(WoS)/ESCI, and EBSCO, publishing peer-reviewed, openly accessible research ideas and grant proposals, and study and trial protocols (also referred to as Registered Report Stage 1 papers). 

In 2024, JMIR Research Protocols received a Journal Impact Factor™ of 1.4 (5-Year Journal Impact Factor™: 1.5) according to the latest release of the Journal Citation Reports™ from Clarivate, 2024. 

With a CiteScore of 2.4, JMIR Research Protocols ranks in the 66th percentile (#211 of 636) as a Q2 journal in the field of General Medicine.

It should be stressed however that most authors do not publish their protocols for "impact" or citations, rather to document their ideas to how to design experiments, to document their successful grant proposals, or to publish (and maybe brag a little about) their already funded protocols (which do not require additional peer-review). We offer this platform for scientists to publish peer-reviewed protocols for a very low APF, and unfunded protocols for a reasonable fee that includes peer-review. 

While the original focus was on eHealth studies, JRP now publishes protocols and grant proposals in all areas of medicine, and their peer-review reports, if available (preliminary results from pilot studies, early results, and formative research should now be published in JMIR Formative Research).

JRP is fully open access, with full-text articles deposited in PubMed Central.

Why should I publish my protocol? 

  • JRP publishes research protocols, grant proposals, pilot/feasibility studies and early reports of ongoing and planned work that encourages collaboration and early feedback, and reduces duplication of effort.
  • JRP will be a valuable educational resource for researchers who want to learn about current research methodologies and how to write a winning grant proposal.
  • JRP creates an early scientific record for researchers who have developed novel methodologies, software, innovations or elaborate protocols.
  • JRP provides a "dry-run" for peer-review of the final results paper, and allows feedback/critique of the methods, often while they still can be fixed.
  • JRP enhances rigor and demonstrates to reviewers of subsequent results papers that authors followed and adhered to carefully developed and described a-priori methods, rather than fishing for P-values (HARKing).
  • JRP facilitates and guarantees subsequent publication of results demonstrating that the methodology has already been reviewed, and reduces the effort of writing up the results, as the protocol can be easily referenced.
  • JRP is compatible with the concept of "Registered Reports" and since May 2018, published protocols receive an International Registered Report Identifier (What is a Registered Report Identifier?) and acceptance of the subsequent results paper is "in principle" guaranteed in any JMIR journal and partner journals - see What is a Registered Report?. We assign an IRRID (International Registered Report Identifier) to each published protocol, faciliating the linking between protocol and final study, and also indicating that results papers of studies are also "in principle accepted" for subsequent publication in other JMIR journals (or other members of the IRRID Registry Network) as long as authors adhere to their original protocol - regardless of study results (even if they are negative), reducing publication bias in medicine.
  • Authors publishing their protocols in JRP will receive a 20% discount on the article processing fee if they publish their results in another journal of the JMIR journal family (for example, JMIR for e-health studies, i-JMR for others).

Need more reasons? Read the Knowledge Base article on "Why should I publish my protocol/grant proposal"!

 

Recent Articles

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Scoping Review Protocols

Manual wheelchairs promote independence among older adult users. However, the user’s level of disability, strength, and stamina, and the environmental conditions in which the wheelchair is used, may limit the functionality of manual wheelchairs and their impact on independence and active aging. The use of power-assist add-ons may mitigate these limitations and allow an individual to age in place.

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Non-Randomized Study Protocols and Methods (Non-eHealth)

A healthful diet in early childhood is essential for healthy growth and disease prevention. Parents influence children’s diets through supportive (eg, structure and autonomy support) and unsupportive (eg, coercive control and indulgence) food parenting practices. Historically, much of this work has focused on parents’ “usual” feeding behaviors using survey methods. However, recent studies using ecological momentary assessment methods have allowed assessment of food parenting behaviors in “real time.” This work has revealed that the practices used by parents to feed children vary across contexts and are influenced by factors such as stress or time constraints. Research is needed to understand the dynamic nature of food parenting and its impact on children’s diets.

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Non-Randomized Study Protocols and Methods (Non-eHealth)

The COVID-19 pandemic has underscored the need for targeted interventions to address health care disparities among specific health care professionals and mitigate the impact of the virus. In response, we developed a comprehensive statewide educational program protocol focused on subject areas of health equity, cultural sensitivity, infection prevention and control (IPC), and quality improvement (QI).

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RCTs - Protocols/Proposals (eHealth)

Only a few trials target high school-aged teens with vaping interventions, typically focusing on prevention rather than cessation, with content limited to vaping harms and refusal skills. Given the co-occurrence and increasing incidence of vaping and mental health issues in teens, both must be simultaneously addressed by vaping interventions.

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Participatory Research Protocols and Proposals

Racism arrived in Australia with colonization and its intentionally oppressive policies and actions toward Aboriginal and Torres Strait Islander Peoples. To a large extent, colonial and biomedical agendas are maintained by Australia’s health system that underlies much of the racialized health inequities in the country. Dentistry significantly lags behind medicine and other health care areas in the uptake of antiracism, with the dental accreditation body only acknowledging racism as a determinant of oral health in 2022.

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Non-randomized Protocols and Methods (ehealth)

Jaw bone density can be altered due to various factors including aging, bone pathologies, hormonal levels, medications affecting bone density, and undue stress posed by parafunctional and adverse habits. Of these factors, chronic areca nut chewing, which creates a heavy load on jaw bones, is a commonly encountered adverse habit in patients. Digital panoramic radiography (OPG) indices are an easy and cost-effective method to evaluate jaw bone density. Index values can also be used as a screening tool for osteoporosis.

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RCTs - Protocols/Proposals (non-eHealth)

Community-based behavior change interventions are a common approach to Water, Sanitation, and Hygiene (WASH). Yet, published evaluations of how these interventions work in district-wide approaches are rare.

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RCTs - Pilots/Feasibility Studies (non-eHealth)

Tinnitus, a common and troublesome symptom of idiopathic sudden sensorineural hearing loss (ISSNHL), is the perception of sound without any external or internal sound source. The etiology of ISSNHL accompanied by tinnitus remains unclear. Tinnitus often occurs alongside or before hearing loss and can severely impact patients’ quality of life, leading to psychological stress and emotional distress. Current treatments primarily focus on improving hearing loss while neglecting tinnitus treatment. Electroacupuncture (EA), a technique widely applied in China for tinnitus management, may become a promising intervention by addressing both auditory and psychological symptoms.

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Proposals (non-eHealth)

Over the past 2 decades, the gut microbiota has emerged as a key player in human health, being involved in many different clinical contexts. Yet, many aspects of the relationship with its host are poorly documented. One obstacle is the substantial variability in wet-laboratory procedures and data processing implemented during gut microbiota studies, which poses a challenge of comparability and potential meta-analysis.

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RCTs - Protocols/Proposals (non-eHealth)

Patients with ischemic stroke are at high risk of recurrence, making preventive care an important factor. Current antiplatelet therapy for recurrence prevention treatment has several limitations. Recent retrospective observational studies suggested that HH333, an herbal prescription, has an inhibitory effect on stroke recurrence in small-vessel diseases.

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RCTs - Protocols/Proposals (non-eHealth)

The treatment of endometriosis includes analgesics, hormone therapy, and surgery. Even after surgical removal of endometriotic lesions, the risk of recurrence remains high once the normal menstrual cycle resumes. Therefore, long-term hormone therapy is essential to prevent recurrence. Among hormonal treatments, low-dose estrogen progestin preparations are not recommended for patients older than 40 years due to the increased risk of thrombotic side effects. In contrast, dienogest does not carry a thrombotic risk, making it a suitable option for older patients. Although dienogest requires long-term administration until menopause in patients with endometriosis, data on its long-term efficacy and potential adverse effects remain limited. In particular, comparative studies assessing the safety and effectiveness of long-term use of dienogest at different doses (1 mg/day vs 2 mg/day) have not been conducted, highlighting the need for further investigation.

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Non-randomized Protocols and Methods (ehealth)

Dry eye disease (DED) is a common ocular condition with diverse and heterogeneous symptoms. Current treatment standards of DED include the post facto management of associated symptoms through topical eye drops. However, there is a need for predictive, preventive, personalized, and participatory medicine. The DryEyeRhythm mobile health app enables real-time data collection on environmental, lifestyle, host, and digital factors in a patient’s daily environment. Combining these data with genetic information from biobanks could enhance our understanding of individual variations and facilitate the development of personalized treatment strategies for DED.

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