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A Multi-Level, Mobile-Enabled Intervention to Promote Physical Activity in Older Adults in the Primary Care Setting (iCanFit 2.0): Protocol for a Cluster Randomized Controlled Trial

A Multi-Level, Mobile-Enabled Intervention to Promote Physical Activity in Older Adults in the Primary Care Setting (iCanFit 2.0): Protocol for a Cluster Randomized Controlled Trial

In this ideal scenario, the total sample size n=398 is required to detect the effect size d=0.25 between the two population means. Second, because the randomization occurs at the clinic level, we need to consider the clustering effect. Previous similar research suggests a small clustering effect due to multiple patients per physician, but virtually no clustering effect between patients with different physicians in the same clinic [45].

Y Alicia Hong, Samuel N Forjuoh, Marcia G Ory, Michael D Reis, Huiyan Sang

JMIR Res Protoc 2017;6(9):e183

Ayurvedic Management of Presbycusis (Project TOPMAC): Protocol for an Exploratory Randomized Controlled Trial

Ayurvedic Management of Presbycusis (Project TOPMAC): Protocol for an Exploratory Randomized Controlled Trial

The administration of the water extract from Ashwagandha (100 mg/kg/d) with drinking water for 8 months has shown to be safe and showed no toxicity in rats [21]. Ashwagandha may operate as a gamma-aminobutyric acid mimetic, cholinomimetic, and agonist for α-7 nicotinic receptors for cognitive function protection [22]. However, no clinical trials or documented data are available on the efficacy of these drugs for presbycusis treatment, despite being widely used in clinics.

Krishna Kumar V, Sanjeev V Thomas, Murugan C Nair, Parvathy G Nair, Nisha M L, Anuradha S, Arunabh Tripathi, Pallavi Mundada, Babita Yadav, B C S Rao, Sudhakar D, Srikanth N

JMIR Res Protoc 2024;13:e55089

Defining the Supportive Care Needs and Psychological Morbidity of Patients With Functioning Versus Nonfunctioning Neuroendocrine Tumors: Protocol for a Phase 1 Trial of a Nurse-Led Online and Phone-Based Intervention

Defining the Supportive Care Needs and Psychological Morbidity of Patients With Functioning Versus Nonfunctioning Neuroendocrine Tumors: Protocol for a Phase 1 Trial of a Nurse-Led Online and Phone-Based Intervention

In the absence of evidence-based guidelines for the SCNS and PROMIS measures, the Cohen d effect size will be calculated and interpreted using existing conventions [51]. If a nonparametric method is required, differences in medians will be examined using the bootstrap percentile method [52]. The number of bootstrap replications will be set at 10,000. All data will be entered in SPSS version 23 or higher (Chicago, IL), and SPSS will be used for scoring, descriptive analysis, and parametric tests.

Lisa Guccione, Karla Gough, Allison Drosdowsky, Krista Fisher, Timothy Price, Nick Pavlakis, Mustafa Khasraw, David Wyld, David Ransom, Grace Kong, Megan Rogers, Simone Leyden, John Leyden, Michael Michael, Penelope Schofield

JMIR Res Protoc 2019;8(12):e14361

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