Long-Term Morbidity and Health After Early Menopause Due to Oophorectomy in Women at Increased Risk of Ovarian Cancer: Protocol for a Nationwide Cross-Sectional Study With Prospective Follow-Up (HARMOny Study)

Lara Terra   ¹ , MSc, MD ;   Maartje J Hooning   ² , MD, PhD ;   Bernadette A M Heemskerk-Gerritsen   ² , PhD ;   Marc van Beurden   ³ , MD, PhD ;   Jeanine E Roeters van Lennep   ⁴ , MD, PhD ;   Helena C van Doorn   ⁵ , MD, PhD ;   Joanne A de Hullu   ⁶ , MD, PhD ;   Constantijne Mom   ⁷ , MD, PhD ;   Eleonora B L van Dorst   ⁸ , MD, PhD ;   Marian J E Mourits   ⁹ , MD, PhD ;   Brigitte F M Slangen   ¹⁰ , MD, PhD ;   Katja N Gaarenstroom   ¹¹ , MD, PhD ;   M Carola Zillikens   ⁴ , MD, PhD ;   Tim Leiner   ¹² , MD, PhD ;   Lizet van der Kolk   ¹³ , MD, PhD ;   Margriet Collee   ¹⁴ , MD, PhD ;   Marijke Wevers   ¹⁵ , MD, PhD ;   Margreet G E M Ausems   ¹⁶ , MD, PhD ;   Klaartje van Engelen   ¹⁷ , MD, PhD ;   Lieke PV Berger   ¹⁸ , MD, PhD ;   Christi J van Asperen   ¹⁹ , MD, PhD ;   Encarna B Gomez-Garcia   ²⁰ , MD, PhD ;   Irma van de Beek   ²¹ , MD, PhD ;   Matti A Rookus   ¹ , PhD ;   Michael Hauptmann   ²² , PhD ;   Eveline M Bleiker   ¹ , PhD ;   Sanne B Schagen   ¹ , PhD ;   Neil K Aaronson   ¹ , PhD ;   Angela H E M Maas   ²³ , MD, PhD ;   Flora E van Leeuwen   ¹ , PhD

¹ Department of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute, Amsterdam, Netherlands

² Department of Medical Oncology, Erasmus University Medical Center, Rotterdam, Netherlands

³ Department of Gynaecology, Antoni van Leeuwenhoek, Amsterdam, Netherlands

⁴ Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, Netherlands

⁵ Department for Gynaecologic Oncology, Erasmus University Medical Center, Rotterdam, Netherlands

⁶ Department for Gynaecology, Radboud University Medical Center, Nijmegen, Netherlands

⁷ Department of Gynaecology, Amsterdam University Medical Centers, Amsterdam, Netherlands

⁸ Department for Gynaecologic Oncology, University Medical Center Utrecht, Utrecht, Netherlands

⁹ Department for Gynaecologic Oncology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands

¹⁰ Department for Gynaecology, Maastricht University Medical Center, Maastricht, Netherlands

¹¹ Department of Gynaecology, Leiden University Medical Center, Leiden, Netherlands

¹² Department Radiology, University Medical Center Utrecht, Utrecht, Netherlands

¹³ Family Cancer Clinic, Netherlands Cancer Institute, Amsterdam, Netherlands

¹⁴ Department for Clinical Genetics, Erasmus University Medical Center, Rotterdam, Netherlands

¹⁵ Department for Clinical Genetics, Radboud University Medical Center, Nijmegen, Netherlands

¹⁶ Division of Laboratories, Pharmacy and Biomedical Genetics, Department of Genetics, University Medical Center Utrecht, Utrecht, Netherlands

¹⁷ Department for Clinical Genetics, Amsterdam University Medical Centers, Vrije University Amsterdam, Amsterdam, Netherlands

¹⁸ Department of Genetics, University Medical Center Groningen, Groningen, Netherlands

¹⁹ Department for Clinical Genetics, Leiden University Medical Center, Leiden, Netherlands

²⁰ Department of Genetics, Maastricht University Medical Center, Maastricht, Netherlands

²¹ Department for Clinical Genetics, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands

²² Brandenburg Medical School Theodor Fontane, Institute of Biostatistics and Registry Research, Neuruppin, Germany

²³ Department of Cardiology, Radboud University Medical Center, Nijmegen, Netherlands