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Improving Early Dementia Detection Among Diverse Older Adults With Cognitive Concerns With the 5-Cog Paradigm: Protocol for a Hybrid Effectiveness-Implementation Clinical Trial

Improving Early Dementia Detection Among Diverse Older Adults With Cognitive Concerns With the 5-Cog Paradigm: Protocol for a Hybrid Effectiveness-Implementation Clinical Trial

Food and Drug Administration–approved medications for dementia Deprescribing anticholinergic medications: discontinuation or nonrenewal of any of the 41 medications in table 7 (“Drugs with strong anticholinergic properties”) of the American Geriatrics Society Beers Criteria [93] Laboratory tests (cognitive indication only): thyroid-stimulating hormone, vitamin B12, glycated hemoglobin, complete blood count, basic metabolic panel, liver tests, HIV antigen and antibody combination, and syphilis immunoglobulin G

Rachel Beth Rosansky Chalmer, Emmeline Ayers, Erica F Weiss, Nicole R Fowler, Andrew Telzak, Diana Summanwar, Jessica Zwerling, Cuiling Wang, Huiping Xu, Richard J Holden, Kevin Fiori, Dustin D French, Celeste Nsubayi, Asif Ansari, Paul Dexter, Anna Higbie, Pratibha Yadav, James M Walker, Harrshavasan Congivaram, Dristi Adhikari, Mairim Melecio-Vazquez, Malaz Boustani, Joe Verghese

JMIR Res Protoc 2025;14:e60471

Acceptability of a Web-Based Health App (PortfolioDiet.app) to Translate a Nutrition Therapy for Cardiovascular Disease in High-Risk Adults: Mixed Methods Randomized Ancillary Pilot Study

Acceptability of a Web-Based Health App (PortfolioDiet.app) to Translate a Nutrition Therapy for Cardiovascular Disease in High-Risk Adults: Mixed Methods Randomized Ancillary Pilot Study

Portfolio Diet.app dashboard with key features highlighted, top to bottom: (A) learn tab that has recipes, tipsheets, and videos; (B) daily average Portfolio Diet Score per month; (C) star rewards, a form of reward for logging into the app and for completing the question of the week; (D) current day total Portfolio Diet Score; (E) specific daily messages related to goals; (F) personal favorite meals for easy tracking; (G) subcategory Portfolio Diet Scores with daily targets of 5 points; (H) progress-tracking

Meaghan E Kavanagh, Laura Chiavaroli, Selina M Quibrantar, Gabrielle Viscardi, Kimberly Ramboanga, Natalie Amlin, Melanie Paquette, Sandhya Sahye-Pudaruth, Darshna Patel, Shannan M Grant, Andrea J Glenn, Sabrina Ayoub-Charette, Andreea Zurbau, Robert G Josse, Vasanti S Malik, Cyril W C Kendall, David J A Jenkins, John L Sievenpiper

JMIR Cardio 2025;9:e58124

Feasibility, Acceptability, and Potential Effects of a Digital Oral Anticancer Agent Intervention: Protocol for a Pilot Randomized Controlled Trial

Feasibility, Acceptability, and Potential Effects of a Digital Oral Anticancer Agent Intervention: Protocol for a Pilot Randomized Controlled Trial

Sample size calculation was undertaken using procedures provided by the software program G*Power 3 [37]. As per our statistical consultant, the calculation was undertaken to determine adequate power in the determination of the potential effects of the intervention (aim 3), in which a repeated-measures ANOVA with a within-between interaction would be the statistical test used.

Saima Ahmed, Christine Maheu, Walter Gotlieb, Gerald Batist, Carmen G Loiselle

JMIR Res Protoc 2025;14:e55475