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JMIR Research Protocols

Protocols, grant proposals, registered reports (RR1)

Editor-in-Chief:

Amy Schwartz, MSc, Ph.D., Scientific Editor at JMIR Publications, Ontario, Canada


Impact Factor 1.6 More information about Impact Factor CiteScore 2.8 More information about CiteScore

JMIR Research Protocols is a unique journal indexed in PubMed, PubMed Central (PMC), MEDLINE, Sherpa Romeo, DOAJ, Scopus, Web of Science(WoS)/ESCI, and EBSCO, publishing peer-reviewed, openly accessible research ideas and grant proposals, and study and trial protocols (also referred to as Registered Report Stage 1 papers). 

It should be stressed however that most authors do not publish their protocols for "impact" or citations, rather to document their ideas to how to design experiments, to document their successful grant proposals, or to publish (and maybe brag a little about) their already funded protocols (which do not require additional peer-review). We offer this platform for scientists to publish peer-reviewed protocols for a very low APF, and unfunded protocols for a reasonable fee that includes peer-review. 

While the original focus was on eHealth studies, JRP now publishes protocols and grant proposals in all areas of medicine, and their peer-review reports, if available (preliminary results from pilot studies, early results, and formative research should now be published in JMIR Formative Research).

JRP is fully open access, with full-text articles deposited in PubMed Central.

Why should I publish my protocol? 

  • JRP publishes research protocols, grant proposals, pilot/feasibility studies and early reports of ongoing and planned work that encourages collaboration and early feedback, and reduces duplication of effort.
  • JRP will be a valuable educational resource for researchers who want to learn about current research methodologies and how to write a winning grant proposal.
  • JRP creates an early scientific record for researchers who have developed novel methodologies, software, innovations or elaborate protocols.
  • JRP provides a "dry-run" for peer-review of the final results paper, and allows feedback/critique of the methods, often while they still can be fixed.
  • JRP enhances rigor and demonstrates to reviewers of subsequent results papers that authors followed and adhered to carefully developed and described a-priori methods, rather than fishing for P-values (HARKing).
  • JRP facilitates and guarantees subsequent publication of results demonstrating that the methodology has already been reviewed, and reduces the effort of writing up the results, as the protocol can be easily referenced.
  • JRP is compatible with the concept of "Registered Reports" and since May 2018, published protocols receive an International Registered Report Identifier (What is a Registered Report Identifier?) and acceptance of the subsequent results paper is "in principle" guaranteed in any JMIR journal and partner journals - see What is a Registered Report?. We assign an IRRID (International Registered Report Identifier) to each published protocol, faciliating the linking between protocol and final study, and also indicating that results papers of studies are also "in principle accepted" for subsequent publication in other JMIR journals (or other members of the IRRID Registry Network) as long as authors adhere to their original protocol - regardless of study results (even if they are negative), reducing publication bias in medicine.
  • Authors publishing their protocols in JRP will receive a 20% discount on the article processing fee if they publish their results in another journal of the JMIR journal family (for example, JMIR for e-health studies, i-JMR for others).

Need more reasons? Read the Knowledge Base article on "Why should I publish my protocol/grant proposal"!

The journal is indexed in PubMed, PubMed Central (PMC), MEDLINE, Sherpa Romeo, DOAJ, Scopus, Web of Science(WoS)/ESCI, and EBSCO.

JMIR Research Protocols received a 2025 Impact Factor of 1.6, ranking Q3 in Public, Environmental & Occupational Health and Health Care Sciences & Services. 

JMIR Research Protocols received a Scopus CiteScore of 2.8 (2025), placing it in the 68th percentile (210/669) as a second quartile (Q2) journal in the field of General Medicine.

Recent Articles

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Scoping Review Protocols

Persistent disparities in diversity, equity, and inclusion (DEI) remain across US residency programs despite recent accreditation requirements. In this context, DEI disparities refer to inequities in the representation, recruitment, advancement, and educational experiences of individuals from underrepresented and marginalized groups. Numerous specialty-specific studies have evaluated DEI content on residency program websites, but these studies differ in their methodologies, assessed content, and reporting practices. There is currently no comprehensive synthesis of how DEI content is presented across the different existing literature in multiple residency specialties. Therefore, a scoping review is needed to map the existing literature.

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Participatory Research Protocols and Proposals

Despite increasing recognition of adolescents’ and young adults’ mental health needs, many young people continue to experience barriers in accessing timely, acceptable, and responsive mental health and psychosocial support (PSS) services. There is a need for contextually relevant and youth-responsive approaches that meaningfully engage young people, caregivers, and service providers in implementation strategy development. The study aims to co-design a mental health and PSS implementation strategy for adolescents and young adults in KwaZulu-Natal (KZN), South Africa, using a human-centered design (HCD) approach.

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Systematic Review Protocols

Large language models (LLMs) are increasingly applied in health care for clinical decision-making, education, and patient communication. However, bias in LLM outputs may exacerbate health care disparities and compromise trust. Despite rapid adoption, there is limited synthesis of how bias is identified, measured, and mitigated in medical applications of LLMs.

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Systematic Review Protocols

Ethics of care lies at the heart of the nursing profession. Grounded in the work of Gilligan and Tronto, it emphasizes relationships and responsiveness to the needs of those receiving care. Although Tronto’s framework specifies 5 elements of care, no systematic synthesis has yet examined how each element is expressed through observable behavioral indicators in the nursing context.

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RCTs - Protocols/Proposals (funded, already peer-reviewed, eHealth)

Smoking is the leading risk factor for postoperative complications and is associated with longer hospital stays, reoperations, and 30-day mortality. Smoking rates among patients undergoing major elective surgery are high (22.3%‐43.0%). It is urgent to identify efficacious, strategically timed smoking cessation interventions for patients undergoing surgery.

Doctor reviews brain MRI scans on a computer monitor, showing detailed axial views of the human brain.
RCTs - Protocols/Proposals (funded, already peer-reviewed, non-eHealth)

Obsessive-compulsive disorder (OCD) is a disabling mental disorder, characterized by obsessions, compulsions, and substantial morbidity. Approximately 50% of adults with OCD fail to achieve satisfactory outcomes from first-line treatments, such as exposure therapy with response prevention (ERP), with or without medication. This leads to chronic social, educational, and occupational impairment. While invasive procedures such as deep brain stimulation are available for severe, treatment-refractory cases, a need remains for less invasive alternatives. Repetitive transcranial magnetic stimulation (rTMS), a noninvasive intervention, shows promise in reducing OCD symptoms. Unlike in depression, rTMS is not yet reimbursed for OCD in the Dutch healthcare system.

Scientist in lab coat and safety glasses using a microscope for research
Methods and Feasibility Studies

Accurate assessment of surgical margins is essential in the treatment of squamous cell carcinoma (SCC) of the upper aerodigestive tract or of cutaneous origin and of basal cell carcinoma (BCC). Intraoperative frozen section analysis is the current reference standard but is time-consuming and requires coordination between surgical and pathology teams. Ex vivo reflectance confocal microscopy offers rapid, real-time evaluation of surgical margins and may provide diagnostic information comparable to frozen section analysis while enabling the development of a reference atlas for tumor visualization.

Two Black female doctors in white coats discuss medical data on a laptop in a clinic.
Scoping Review Protocols

The African continent has witnessed a notable shift in its economic landscape, marked by a significant rise in unemployment and a parallel surge in informal trading activities. In response to economic challenges, a substantial number of women within the informal trading sector in African countries have ventured beyond their home settings to engage in trading, aiming to alleviate poverty within their households. However, this pursuit is often characterized by conditions of poverty and socioeconomic difficulties. These women frequently lack access to fundamental health care and social protection services, and they operate within environments that are suboptimal for health and safety. This highlights a gap in knowledge regarding their challenges and barriers in accessing health care and an opportunity for better understanding.

Scientist holding a test tube with liquid and a wire in a lab
Non-Randomized Study Protocols and Methods (Non-eHealth)

Stainless steel (SS) orthodontic archwires are widely used because of their mechanical properties, affordability, and biocompatibility; yet, prolonged intraoral exposure can cause electrochemical corrosion and release of metal ions (eg, Ni and Cr) that may affect clinical performance and patient safety. Surface coatings such as silver dioxide have been proposed to improve corrosion resistance, but comparative data for silver dioxide–coated versus uncoated SS orthodontic archwires across clinically relevant simulated oral environments are lacking.

Young boy using a smartphone on a dusty soccer field in Africa
Non-Randomized Studies (funded, eHealth)

Adolescent mental health care is constrained not only by limited treatment capacity but also by the absence of precise and efficient tools to identify and triage those in need. Measurement-based mental health care relies on standardized assessments to guide identification, treatment selection, and ongoing monitoring of mental disorders. However, conventional assessments present a trade-off: diagnostic interviews lack feasibility at scale, while brief screening tools result in misclassification and suboptimal allocation of limited mental health resources. Computerized adaptive testing addresses this trade-off by dynamically tailoring assessments to individuals, maximizing measurement precision while minimizing assessment burden. Despite these advances, no adaptive assessment for adolescent mental health has been developed or calibrated using African data.

Person holding a smartphone displaying the Jooy app logo
Grant Proposals (eHealth, funded)

Leisure participation is essential for children’s health and well-being and is also a fundamental human right; however, children and youth with disabilities face significant barriers to participation compared with their peers without disabilities. The Jooay App was developed to address gaps in information and access to adaptive and inclusive leisure activities. A new gamification-based version of the Jooay App was co-designed with users, including youth with disabilities, parents, and health care professionals.

Man in glasses and blue shirt sits in a doctor's waiting room.
Scoping Review Protocols

Black, Caribbean, and African immigrant communities in Canada face compounding systemic inequities that undermine mental well-being and limit access to culturally grounded mental health promotion (MHP) strategies. Despite growing national policy attention to these disparities, the landscape of MHP programs and initiatives developed for, with, or by Black, Caribbean, and African populations remains fragmented and poorly synthesized.

Preprints Open for Peer Review

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This journal is indexed in

  • PubMed
  • PubMed CentralMEDLINE
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  • ScopusDOAJDOAJ Seal
    Sherpa RomeoEBSCO/EBSCO Essentials

  • Web of Science - ESCI