JMIR Research Protocols

Health care professionals play a crucial role in executing, supporting, and assessing quality improvement programs. Clearly defined competencies in health care quality are essential for optimal performance and serve as the foundation for both quality practice and the design of a capacity development program.

Low anterior resection syndrome (LARS) is a common functional problem after sphincter-preserving rectal cancer surgery and includes urgency, frequent bowel movements, clustering, and fecal incontinence. Diverting ileostomy may further disrupt the intestinal environment and alter the gut microbiota, potentially worsening bowel dysfunction after ileostomy closure. However, evidence remains limited on whether bowel stimulation with probiotics before ileostomy closure can improve postoperative bowel function and reduce LARS severity.

Persistent postconcussion symptoms (PPCSs) represent a complex phenomenon following mild traumatic brain injury (mTBI), and this phenomenon is characterized by a diverse range of symptoms that greatly impact daily functioning, including the ability to engage in physical, cognitive, and social activities. Effective rehabilitation strategies and a nuanced understanding of brain function and patient perception remain insufficiently explored in adults with PPCSs.

Despite the existence of several regional registries in the United Kingdom, gaps in geographic coverage have limited the ability to produce accurate national estimates of incidence, prevalence, and regional variation for motor neuron disease (MND). To address these challenges, a comprehensive national register encompassing England, Wales, and Northern Ireland was established to support epidemiological studies, health care planning, and clinical research.

Approximately 80% of individuals with Parkinson disease (PD) experience impaired balance and mobility, contributing to freezing of gait, an increased risk of falls, and reduced health-related quality of life. Mind-body interventions, such as mindfulness and yoga, may address both motor and nonmotor symptoms by enhancing mind-body coordination and reducing stress, thereby offering a scalable approach to balance rehabilitation in PD.

Extended time on academic exams is one of the most frequently granted accommodations for students with attention-deficit/hyperactivity disorder. However, there is a lack of empirical evidence supporting its effectiveness, particularly in the college population.

Burnout and poor well-being are serious problems in the workforce all over the world. Especially in academia, high pressure is evident. Therefore, addressing burnout is essential for enhancing academic staff well-being. Acceptance and commitment therapy (ACT), which aims to enhance psychological flexibility skills comprising present moment awareness, value-based actions, and differentiation of thoughts from self, has been found to be a promising approach to enhance workers well-being and work satisfaction.

Chronic pain affects approximately 1 in 5 adults worldwide and imposes a major personal and societal burden. Supported self-management, increasingly delivered through digital health systems, is recommended to improve quality of life and function. Dual-facing digital health systems (DDHSs), which engage both patients and professionals, show promise but remain underexplored, with limited use of established frameworks to guide their design and evaluation.

Clinical skills deficits are a patient-safety concern, yet remediation remains underexamined, particularly in low- and middle-income countries, where faculty shortages, uneven access to simulation and supervised practice, inconsistent assessment, and stigma can hinder timely and effective support. The effects of trainee underperformance extend beyond the individual, with implications for patient care, supervisory workload, and team functioning. Although interest in remediation is increasing, the evidence base remains fragmented, dominated by high-income settings, and largely descriptive. A theory-driven review is therefore needed to explain how remediation works, for whom, and under what conditions.

Influenza, a highly contagious acute respiratory illness, causes annual seasonal epidemics worldwide, imposing a substantial public health burden. Although neuraminidase inhibitors, such as oseltamivir, can shorten symptom duration, their use is limited by antiviral resistance and adverse reactions. Kanggan mixture (KGM), an in-hospital traditional Chinese medicine preparation at Jiangsu Province Hospital of Chinese Medicine, has been widely used in clinical practice for influenza treatment, showing favorable effects on fever reduction and symptom improvement; however, high-quality comparative evidence on the efficacy and safety of KGM remains limited. This study is designed to address this gap by evaluating whether KGM is noninferior to oseltamivir for the treatment of influenza.

Hispanic adults with type 1 diabetes (T1D) have suboptimal access to continuous glucose monitoring (CGM). Widening access to and increasing uptake of CGM for Hispanic adults with T1D are warranted.

Intensive care units (ICUs) present a highly stressful environment for patients, relatives, and health care professionals, often resulting in psychological distress. Despite the well-documented psychosocial burden, there is a lack of low-threshold, integrated support structures for all target groups. Based on the findings of phase A, a complex intervention was developed involving the permanent integration of study therapists into ICU teams.