Non-Randomized Study Protocols and Methods (Non-eHealth)

Factors Associated With Loss to Follow-Up Among People Living With HIV in a National Tertiary Care Hospital: Protocol and Baseline Analysis of a Prospective Cohort Study

Luis Eduardo Del Moral Trinidad, Jaime Federico Andrade Villanueva, Luis Alberto Ruíz Mora, Carlos Valentino García y Nuño, Maria Fernanda Perez Quintero, Brian Eduardo Apodaca Escalante, Jocelyn Graciela Torres Arias, Juan Pablo Martínez Herrera, Melva Guadalupe Herrera Godina, Luz Alicia González Hernández

JMIR Res Protoc 2026 (Mar 18); 15:e76470

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Molecular and Pharmacogenetic Marker Evaluation in Relation to the Toxicity and Clinical Response of Acute Lymphoblastic Leukemia Treatment in Indian Children (MPGx-INDALL): Protocol for a Prospective Observational Cohort Study

Swetambri Sharma, Shuvadeep Ganguly, Kamali Murugadoss, Smita Kayal, Swaminathan Keerthivasagam, Jaikumar Ramamoorthy, Archna Singh, Deepam Pushpam, Jayanthi Mathaiyan, Yvonne Gloor, Frederic Baleydier, Marc Ansari, Sameer Bakhshi, Biswajit Dubashi, Chakradhara Rao S Uppugunduri

JMIR Res Protoc 2026 (Mar 17); 15:e79865

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Self-Management Support After Burns: Protocol for a Multicenter, Stepped-Wedge Hybrid Type II Effectiveness-Implementation Study

Sharon L Blok, Marianne K Nieuwenhuis, Sonja M H J Scholten-Jaegers, Irma Visser, Raaba S M Thambithurai, Monique A C M de Craen-de Moor, Kiran C Baran, Anuschka S Niemeijer, Eelke Bosma, Corry K van der Sluis, Sven J G Geelen, National Burn Care, Education & Research Group, The Netherlands

JMIR Res Protoc 2026 (Mar 16); 15:e86671

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Perceptions of Abortion and Sexual and Reproductive Health in Chilean Medical and Midwifery Education: Protocol for a Mixed Methods Study

Lidia Casas-Becerra, Alejandra Ramm, Beatriz Pérez, Heidy Kaune, Mercedes Carrasco-Portiño, Adela Montero, Cecilia Bustos-Ibarra, Henry Castro-Arias, Claudio López-Labarca, Leonardo Reyes-Torres

JMIR Res Protoc 2026 (Mar 06); 15:e81427

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Factors That Influence Patients’ Decisions About Repetitive Transcranial Magnetic Stimulation as a Treatment Option for Treatment-Resistant Depression: Protocol for a Prospective Mixed Methods Cohort Study

Alexandra Godinho, Sanvitti Dalmia, Steven Selchen, Daniel Tziatis, Pete Wegier

JMIR Res Protoc 2026 (Mar 06); 15:e82491

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3D Comparative Evaluation of Condylar Morphology Between Chronic Areca Nut Chewers and Nonchewers: Protocol for a Case-Control Study

Vaishnavi Tarpe, Suwarna Dangore Khasbage

JMIR Res Protoc 2026 (Mar 06); 15:e84038

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Effects of Time-Restricted Eating on Ketone Metabolism and Immunoregulation in Premenopausal Women: Protocol for a Pilot, Prospective, Single-Arm Dietary Intervention Study

Geethika P Thota, Natalie A Macheret, Sophia B Glaros, Ila N Kacker, Samson L Cantor, Lilian Mabundo, Noemi Malandrino, Kong Y Chen, Amber B Courville, Sara Turner, Shanna Yang, Andrea Krenek, Thomas C Recupero, Rachael J Klein, Kim Han, Patrycja Puchalska, Peter Crawford, Michael N Sack, Stephanie T Chung

JMIR Res Protoc 2026 (Mar 06); 15:e81063

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Safety of Administration of Vasopressors Through Peripheral Compared to Central Venous Catheters in a Rural Kenyan Hospital: Protocol for a Prospective Observational Cohort Study

Grace Hezi Gao, Brian Kimani, Linette Lepore, Zahra Aghababa, Hannah Gitura, Michael Kinuthia, Jack Musau, Judy Muthoki, Alice Mwonge, Fredrick Ndibaru, Ann Viola Ndubi, Juliah Ndungu, Kinzi Nixon, Moses Odhiambo, Winslet Okari, Benjamin Thairu, Lilian Vihenda, Rachel M Wojcik, B Jason Brotherton, Kristina E Rudd

JMIR Res Protoc 2026 (Mar 05); 15:e81794

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Disease Progression and Outcomes in Patients With Benign Prostatic Hyperplasia: Protocol for a Multicenter Retrospective Cohort Study

Zexuan Lv, Jiaxing Liu, Yin Lu, Xu Zhang, Fan Gao, Bingyang Guo, Hongyu Zhang, Hongzhao Li, Chao Lv

JMIR Res Protoc 2026 (Mar 02); 15:e84965

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Evaluation of the Antimicrobial Efficacy of Cerium Oxide Nanoparticles and Chlorhexidine Gluconate Against Enterococcus faecalis in Root Canal Systems: Protocol for an In Vitro Study

Bhuvaneshwari Shrikant Khanadali, Anuja Ikhar

JMIR Res Protoc 2026 (Mar 02); 15:e77998

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A Novel Social Network Approach to Measure Intersectional Stigma Among Latino Men Who Have Sex With Men in San Diego, California (NEXUS): Protocol for a Longitudinal Cohort Study

Laramie R Smith, Angel B Algarin, Eileen V Pitpitan, Heather A Pines, Nicole K Kelly, Carl Latkin, Aaron Gutierrez, Maryam Hussain, Francisco Soto, Ricardo Vazquez Jr, Stevie Juarez, Albert Genegaling, Rosalinda Rodriguez, Anthony Cirilo, Juan Esparza, Saul Cruz, Erick Jimenez, Ulises Reyes, Veronica Moore, Malek Guerbaoui, Beth Davenport, Jeannette Aldous, Katherine Penniga, Kenyatta Parker, Britt Skaathun

JMIR Res Protoc 2026 (Feb 27); 15:e72334

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Differentiating the COVID-19 Infection and Vaccine Experiences of Patients With Systemic, Single Organ, and Overlap Immune-Mediated Inflammatory Disease: Protocol for a Secondary Analysis for Enhancing COVID-19 Vaccine Pharmacovigilance

Meredith Leston, José M Ordóñez-Mena, Xinchun Gu, Mark Joy, F D Richard Hobbs, Lennard Y W Lee, Ioannis Parodis, Laura Andreoli, Nelly Ziade, Latika Gupta, Vikas Agarwal, Richard Conway, John Isaacs, Jeffrey Curtis, Alessia Alunno, Stefan Siebert, Ori Elkayam, Karen Schreiber, Simon de Lusignan

JMIR Res Protoc 2026 (Feb 27); 15:e68785

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GORE VIABAHN VBX Balloon-Expandable Endoprostheses as a Bridging Stent With Branched and Fenestrated Endografts in the Endovascular Treatment of Aortic Aneurysms: Protocol for a Retrospective Multicenter Registry (EMBRACE Study)

Pietro Dioni, Anders Wanhainen, Jacob Budtz-Lilly, Nuno Dias, Tab Bonny, Luca Bertoglio, EMBRACE study investigator

JMIR Res Protoc 2026 (Feb 27); 15:e78970

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Educational Intervention to Improve Sexual Health and Quality of Life in Survivors of Breast and Gynecological Cancer: Protocol for a Mixed Methods Feasibility Study

Nathalia Salazar Falla, María de los Ángeles Navas Jojoa, Juan David Lalinde Riviño, Auramaría Escandón Bucheli, Juan Sebastián Galindo-Sánchez

JMIR Res Protoc 2026 (Feb 27); 15:e80567

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Using Textural Analysis of Thermal Imaging to Predict Healing Status of Diabetes-Related Neuropathic Foot Ulcers: Protocol for a Co-Design and Longitudinal Study

Kate Waller, Rajna Ogrin, Quoc Cuong Ngo, Barbara Polus, Samantha Hanna, Aye Nyein Tint, Richard J MacIsaac, Anna Galligan, Elif Ilhan Ekinci, Dinesh Kumar

JMIR Res Protoc 2026 (Feb 26); 15:e69793

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Implementation of a Personalized Medicine Approach in Patients With Type 2 Diabetes Mellitus Receiving Multiple Daily Insulin Injections (POMA Project): Protocol for a Before-and-After Intervention Study

Rosa Giné-Balcells, Bogdan Vlacho, Olga Carmen Vidal-Pérez, Albert Lecube, Josep Franch-Nadal, Dídac Mauricio, Àngels Molló-Iniesta, Marta Hernández, POMA Study Group

JMIR Res Protoc 2026 (Feb 24); 15:e85375

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Stereotactic Adaptive Radiation Therapy for Borderline Resectable or Locally Advanced Pancreatic Cancer to Minimize Gastrointestinal Toxicity (ARTIA-Pancreas): Protocol for a Single-Arm Prospective Trial

Lauren E Henke, Hyun Kim, Eric Laugeman, Steven Kohlmyer, Claire McCann, Kate Pietrovito, Kenneth Russell, Jennifer Woo, Alex T Price

JMIR Res Protoc 2026 (Feb 23); 15:e84607

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Analysis of Associated Factors and Construction of Risk Prediction Models for Frailty in Hospitalized Older Adults Living With HIV: Protocol for a Prospective Observational Study

Fan Li, Chaoying Xie, Fang Xiang

JMIR Res Protoc 2026 (Feb 19); 15:e84271

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In Vitro Comparison of the Dimensional Accuracy of Implant Impressions Using Custom Acrylic Trays and Prefabricated Self-Perforating Trays: Protocol for a Comparative Evaluation Study

Arti Agrawal, Sharayu Nimonkar, Surekha Godbole, Rushabh Parakh, Vikram Belkhode, Namita Zilpilwar

JMIR Res Protoc 2026 (Feb 19); 15:e79452

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Establishing Reference Intervals for Fat-Soluble Vitamins in Healthy Chinese Adults: Study Protocol for a Cross-Sectional, Multicenter Study

Zhong Liu, Chenbing Liu, Nan Li, Chao Shen, Lihong Qiu, Di Sheng

JMIR Res Protoc 2026 (Feb 17); 15:e80425

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