Non-Randomized Study Protocols and Methods (Non-eHealth)

Articles published in 2026 in this theme: 91 (scroll down to load remaining articles)

2026

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Community Health and Demographic Surveillance System for Noncommunicable Disease Epidemiology Among Adults in Rural and Urban Zimbabwe, 2024-2029: Protocol for a Longitudinal Surveillance Study

Richard Makurumidze, Terrence Rudado Musekiwa, Justice Mudavanhu, Newten Handireketi, Manes Munyanyi, Cremance Tshuma, Marvellous Mhloyi, Justen Manasa, Jonathan Arthur Matenga, Simbarashe Rusakaniko

JMIR Res Protoc 2026 (Jul 10); 15:e89292

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Novel Multiplex Near–Point-of-Care PCR Assay for Detecting Sexually Transmitted Infections Among PrEP Users in Western Kenya: Protocol for a Cross-Sectional Pilot Study With an Epidemiological Assessment

Aarman Sohaili, Felix Mogaka, Zoïe Alexiou, Victor Ocholla Omollo, Servaas A Morre, Elizabeth Anne Bukusi, Pierre P M Thomas

JMIR Res Protoc 2026 (Jul 10); 15:e80643

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Single-Dose Longitudinal Pharmacokinetic Evaluation of Doravirine in Pregnant Women Living With HIV: Protocol for a Phase 1 Study

Amanda Poliseno, Lisa Rahangdale, Cynthia Gay, Emma Trawick Roberts, Angela Kashuba

JMIR Res Protoc 2026 (Jul 10); 15:e89990

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Velopharyngeal Anatomy and Speech Production in Cleft Palate Surrounding Primary Palatoplasty: Protocol for a Prospective Observational Pilot Study

Katelyn Kotlarek, Gregory Allen, Ilana Neuberger, Kate Bunton

JMIR Res Protoc 2026 (Jul 10); 15:e97206

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Pneumococcal Vaccination Uptake in People With Immunosuppressed Conditions Using Real-World Primary Care Data Across England: Protocol for a Retrospective Descriptive Study

Bernardo Meza, Gavin Jamie, Jose Ordóñez-Mena, Rachel Byford, Timea Suli, Michael Bride, Benoît Corriveau, Martin Whyte, Mark Joy, Simon de Lusignan, Michael Feher

JMIR Res Protoc 2026 (Jul 09); 15:e92266

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Yiqi Fumai Lyophilized Injection for Improving Exercise Tolerance in Chronic Heart Failure: Protocol for a Prospective Cohort Study

Yiming Zuo, Yunfeng Jia, Lu Fan, Yayi Liu, Yuxiao Cao, Miaomiao Wei, Lei Wei, Xiaoling Wang, Xuezheng Liu, Shichao Lv

JMIR Res Protoc 2026 (Jul 07); 15:e91051

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Characterizing the Epidemiology of Influenza A Viruses at the Swine-Human Interface: Study Protocol of the PigFluCam+ Project in Cambodia

Hannah Holt, Arata Hidano, William T M Leung, Monivan Chhour, Sokmony Yib, Monidarin Chou, Vonthanak Saphonn, Chan Leakhena Phoeung, Ty Chhay, Sothyra Tum, Sina Vor, Sokchea Huy, San Sorn, Foong Ying Wong, Michael Zeller, Gavin J D Smith, Yvonne C F Su, James W Rudge

JMIR Res Protoc 2026 (Jul 07); 15:e67870

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An Innovative Model of Stroke Care for Rapid Assessment and Discharge of Patients With Transient Ischemic Attack and Stroke in Northeastern Ontario: Protocol for the Implementation and Evaluation of MOTIVE (Mobile Transient Ischemic Attack and Stroke With Adaptive Workflow) Team

Venkadesan Rajendran, Chantal Liddard, Lisa Zeman, Susan Bursey, Ravinder-Jeet Singh

JMIR Res Protoc 2026 (Jul 03); 15:e93315

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Identification of Potentially Inappropriate Medications for Adults Below 65 Years: Protocol for a Modified Delphi Study

Eva Filosa, Nicole Schönenberger, Utibe R Essien, Camille Gagnon, Danijela Gnjidic, Lisa Kouladjian O’Donnell, Elizabeth Manias, Lisa M McCarthy, Frank Moriarty, Jérôme Nguyen-Soenen, Sion Scott, Michael A Steinman, Petra A Thürmann, Marnie Goodwin Wilson, Bianca J Gutman, Arielle Mendel, Emilie Trinh, Todd C Lee, Emily G McDonald

JMIR Res Protoc 2026 (Jul 03); 15:e92082

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Cost-Effectiveness Analysis of Age-Specific N-Terminal Pro-B-Type Natriuretic Peptide Thresholds for Heart Failure Diagnosis in China: Protocol for a Markov Model–Based Study

Jing Wang, Changyuan Liu, Shuangning Ding, Yongze Li

JMIR Res Protoc 2026 (Jun 29); 15:e95071

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Evaluation of the Efficacy of Human Papillomavirus Screening Compared With Cytology Screening in Pregnant Women: Protocol for a Prospective Multicenter Trial

Risa Matsunaga, Jun Tamura, Kouji Yamamoto, Kotaro Senuki, Reo Tanoshima, Etsuko Miyagi, Taichi Mizushima

JMIR Res Protoc 2026 (Jun 25); 15:e86397

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KlimaNot—Effects of Climate Change on Emergency and Acute Care: Protocol for a Multicenter, Registry-Based Observational Cohort Study

Kai Heimrath, Mirjam Rupprecht, Madlen Schranz, Timon Klein, Jenny Unterkofler, Tobias Schilling, Jonas Bienzeisler, Miriam Hertwig, Johannah Cramer, Merle Potzauf, Thea Laurentius, Wiebke Schirrmeister, Cornelius Bollheimer, Sebastian Sager, Rainer Röhrig, Felix Walcher

JMIR Res Protoc 2026 (Jun 25); 15:e82267

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Investigating the Association Between Volatile Organic Compounds and Preterm Birth in Detroit, Michigan: Protocol for the Center for Leadership in Environmental Awareness and Research Birth Cohort Study

Andrea E Cassidy-Bushrow, Albert M Levin, Mei Lu, Jennifer K Straughen, Emily Leydet

JMIR Res Protoc 2026 (Jun 24); 15:e87272

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Adaptation of the Transition Readiness Assessment Questionnaire for Pediatric-Onset Multiple Sclerosis: Protocol for a User-Centered Design Approach

Claudia Gambrah-Lyles, Aaron W Abrams, Kelsey E Poisson, Kristen S Fisher, Kimberly A O'Neill, Akash Virupakshaiah, Sara Loud, Hollie Schmidt, Melissa Wright, Emily Blosberg, John W Rose

JMIR Res Protoc 2026 (Jun 24); 15:e91763

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Quantitative Postural Evaluation in Orchestral Musicians (the OPErA Project): Protocol for a Cross-Sectional Study

Claudia Consentino, Marina Ramella, Sara Da Pian, Alessandro Gastaldelli, Pier Carlo Battain, Rosa Maria Converti

JMIR Res Protoc 2026 (Jun 22); 15:e81885

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Dovramilast for Erythema Nodosum Leprosum in Patients With Leprosy in Nepal: Protocol for a Phase 2 Open-Label Pilot Study

Mahesh Shah, Divya RSJB Rana, Kapil Dev Neupane, Preeti Maharjan, Suwash Baral, Reejana Shrestha, Jivan Shakya, Binod Aryal, Bishwanath Acharya, Indra Bahadur Napit, Deanna A Hagge

JMIR Res Protoc 2026 (Jun 17); 15:e88069

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Prevalence of and Risk Factors for Metabolic Syndrome, Vascular Damage, and Accelerated Aging (MetVasA) After Pediatric Hematopoietic Stem Cell Transplantation for Hematological Malignancy: Protocol for a Cross-Sectional Cohort Study

Lisa J Asbroek, Helena JH van der Pal, Marta Fiocco, Elizabeth AM Feijen, Lucienne H Grundeken, Maria MW Koopman, Raphaële RL van Litsenburg, Patrick van der Torre, Jan Westerink, Leontien CM Kremer, Saskia MF Pluijm, Dorine Bresters

JMIR Res Protoc 2026 (Jun 16); 15:e77429

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Practice Areas, Skills, and Core Competencies of Advanced Practice Physiotherapists Working in Tertiary Care in Germany: Protocol for a 3-Round Delphi Study to Establish Expert Consensus

Lukas Kühn, Leonie Heimken, Lena Frenz, Annalena Paus

JMIR Res Protoc 2026 (Jun 11); 15:e90704

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Safety and Effectiveness of an Integrative Treatment of Acupuncture-Based Intervention in Survivors of Breast Cancer With Postmastectomy Pain Syndrome: Protocol for a Single-Center, Single-Arm Exploratory Trial

Naruaki Kawasaki, Hiroto Ishiki, Naho Matsubara, Takako Ikegami, Ayaka Ishikawa, Sayaka Arakawa, Asuka Takahashi, Tomoko Uchida, Yukie Nameki, Yoko Horiguchi, Takeshi Murata, Shin Takayama, Akihiko Suto, Kota Kihara, Keisuke Ariyoshi, Shunsuke Oyamada, Ayako Kayano, Hiromichi Matsuoka, Tatsuya Takagi, Eriko Satomi

JMIR Res Protoc 2026 (Jun 11); 15:e94381

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Dose Recommendations for Drugs in Patients With Liver Cirrhosis (The ALIVe Study): Protocol for a Multiphase Validation and Consensus Study

Katharina Karsten Dafonte, Philipp Lutz, Christian Jansen, Christian P Strassburg, Robert Németh, Gunther Hartmann, Ulrich Jaehde, Martin Coenen

JMIR Res Protoc 2026 (Jun 09); 15:e89042

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