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A Multicomponent Strategy to Improve HIV Pre-Exposure Prophylaxis in a Southern US Jail: Protocol for a Type 3 Hybrid Implementation-Effectiveness Trial

A Multicomponent Strategy to Improve HIV Pre-Exposure Prophylaxis in a Southern US Jail: Protocol for a Type 3 Hybrid Implementation-Effectiveness Trial

Of over 12,000 HIV/STI tests performed each year at the DCJ, there are approximately 50 to 100 new HIV diagnoses (personal communication by Dr Barry-Lewis Harris, April 2024) and high STI positivity (5% syphilis, 5% gonorrhea, and 11% chlamydia) [35,66], which is a recommended indication for Pr EP use. The approach to HIV testing at the DCJ is a combination of opt-in and opt-out.

Ank E Nijhawan, Jana Kholy, Julia L Marcus, Timothy P Hogan, Robin T Higashi, Jacqueline Naeem, Laura Hansen, Brynn Torres, Barry-Lewis Harris, Song Zhang, Douglas Krakower

JMIR Res Protoc 2025;14:e64813