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Effectiveness of Stromal Vascular Fraction (SVF) and Platelet-Rich Plasma (PRP) in Patients With Knee Osteoarthritis: Protocol for a Phase 3, Prospective, Randomized, Controlled, Multicenter Study (SPOST Study)

Effectiveness of Stromal Vascular Fraction (SVF) and Platelet-Rich Plasma (PRP) in Patients With Knee Osteoarthritis: Protocol for a Phase 3, Prospective, Randomized, Controlled, Multicenter Study (SPOST Study)

AD-MSCs seem to have a better hypoxic tolerance, fewer immunologic and inflammatory responses [14], better chondrogenic induction and gene expression [15], and less variable and more reliable clinical result [14] than bone marrow–derived mesenchymal stem cells (B-MSC). Stromal vascular fraction (SVF), a product from processed adipose tissue, contains MSCs, endothelial precursor cells, T regulatory cells, macrophages, smooth muscle cells, pericytes, and preadipocytes.

Adrien Schwitzguebel, David Andres Ramirez Cadavid, Tamara Da Silva, Pierre Decavel, Charles Benaim

JMIR Res Protoc 2025;14:e62659

Assessing the Cultural Fit of a Digital Sleep Intervention for Refugees in Germany: Qualitative Study

Assessing the Cultural Fit of a Digital Sleep Intervention for Refugees in Germany: Qualitative Study

Frequency analyses of positive and negative feedback given by the refugees from (A) Ukraine and (B) other countries of origin participating in the qualitative study in Germany. The numbers of positive and negative feedback are illustrated separately for the adapted version and the nonadapted version of the digital intervention Sleep-e tested in the study. oth: other countries of origin; ukr: Ukraine. You can take a lot from it also. And you can learn easily also. To have the training..., it’s much easier.

Maja Blomenkamp, Andrea Kiesel, Harald Baumeister, Dirk Lehr, Josef Unterrainer, Lasse B Sander, Kerstin Spanhel

JMIR Form Res 2025;9:e65412

The Effect of Nurse Navigators in Digital Remote Monitoring in Cancer Care: Case Study Using Structural Equation Modeling

The Effect of Nurse Navigators in Digital Remote Monitoring in Cancer Care: Case Study Using Structural Equation Modeling

Screenshots of the patient smartphone app (A) and nurse navigators’ dashboard (B). The role of NN interventions in outcomes, including toxicity, hospitalization length, and emergency service visits, was explored using a structural equation modeling approach. As shown in Figure 2, the framework used draws inspiration from the De Lone and Mc Lean [16] model, which explains the success of information systems like DRM based on the roles of system quality, user satisfaction, and use.

Etienne Minvielle, Joel Perez-Torrents, Israa Salma, Philippe Aegerter, Marie Ferrua, Charles Ferté, Henri Leleu, Delphine Mathivon, Claude Sicotte, Mario Di Palma, Florian Scotté

J Med Internet Res 2025;27:e66275