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All analyses were carried out in R supplemented by R Studio (version 2023.12.1.402; R Foundation for Statistical Computing), except for the power calculation for which G*Power (version 3.1; Heinrich Heine University Düsseldorf) was used. Multiple packages were used to supplement analysis and visualization, these include but are not limited to: dplyr [41], vioplot [42], ggplot2 [43], psych [44], rstatix [45], ggeffects [46], ordinal [47], and VGAM [48].
JMIR Form Res 2025;9:e68132
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Our analyses, based on simulated data, suggest that a total sample size of 300 provides enough statistical power (up to 90%) to detect anticipated effect sizes on primary outcomes of cognitive capacity and cognitive bias based on values from our group and those reported in the literature (CR: d=0.50 and MCT: g=0.27) [9,20,27,31]. The attrition rate for our digital groups has been approximately 20%; we will nonetheless conservatively adjust for an attrition rate of 30%.
JMIR Res Protoc 2025;14:e63269
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Evaluating User Experience and Satisfaction in a Concussion Rehabilitation App: Usability Study
JMIR Form Res 2025;9:e67275
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Then, participants consumed a fixed liquid meal (Ensure Plus, Abbott Nutrition; 900 kcal in 660 g of fluid: 30% fat, 15% protein, and 55% carbohydrate) from –5 to 0 minutes. To capture GLP-1 and insulin responses to the fixed meal, 2 ml blood samples were drawn at +5, +15, and +30 minutes. Momentary ratings were completed immediately before each blood draw.
JMIR Res Protoc 2025;14:e66554
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