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Theory-Based Social Media Intervention for Nonmedical Use of Prescription Opioids in Young Adults: Protocol for a Randomized Controlled Trial

Theory-Based Social Media Intervention for Nonmedical Use of Prescription Opioids in Young Adults: Protocol for a Randomized Controlled Trial

Eligible leaders will be those who are (1) aged between 18 and 25 years, (2) formally trained as a recovery coach (>40 h), (3) have had successful recovery from opioid misuse or opioid use disorder, and (4) use social media (eg, Instagram, Facebook, and Snapchat) on a daily basis.

Cheuk Chi Tam, Sean D Young, Sayward Harrison, Xiaoming Li, Alain H Litwin

JMIR Res Protoc 2025;14:e65847

Examining the Efficacy of the Telehealth Assessment and Skill-Building Kit (TASK III) Intervention for Stroke Caregivers: Protocol for a Randomized Controlled Clinical Trial

Examining the Efficacy of the Telehealth Assessment and Skill-Building Kit (TASK III) Intervention for Stroke Caregivers: Protocol for a Randomized Controlled Clinical Trial

Caregivers will be randomly assigned 1:1 to the TASK III or ISR group using a permuted block randomization stratified by type of relationship (spouse vs adult child or other) and baseline depressive symptoms (nondepressed vs depressed, with a PHQ-9 score ≥5) as in the TASK II trial [34]. Random permutations within each block within each stratum will be generated using a random number generator (SAS Proc Plan; SAS Institute).

Tamilyn Bakas, Elaine Miller, Heidi Sucharew, Natalie Kreitzer, Jahmeel Israel, Matthew Rota, Brett Harnett, Kari Dunning, Holly Jones, Michael McCarthy, Bonnie Brehm, Joan K Austin, Pamela H Mitchell

JMIR Res Protoc 2025;14:e67219