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Developing an Online Community Advisory Board (CAB) of Parents From Social Media to Co-Design an Human Papillomavirus Vaccine Intervention: Participatory Research Study

Developing an Online Community Advisory Board (CAB) of Parents From Social Media to Co-Design an Human Papillomavirus Vaccine Intervention: Participatory Research Study

Community advisory boards (CABs) are a widely integrated methodology in participatory health research to understand community needs, advise research, and ultimately improve health behaviors or health outcomes [1]. Comprising community members, leaders, stakeholders, and others, CABs are united by a common health interest, identity, status, or experience [2].

Regan M Murray, Shawn C Chiang, Ann C Klassen, Jennifer A Manganello, Amy E Leader, Wen-Juo Lo, Philip M Massey

JMIR Form Res 2025;9:e65986

The Added Value of Digital Body Chart Pain Surface Assessment as an Objective Biomarker: Multicohort Study

The Added Value of Digital Body Chart Pain Surface Assessment as an Objective Biomarker: Multicohort Study

A significant correlation and overlap between pain intensity and pain surface would suggest that measuring pain intensity alone is sufficient, while a lack of correlation and overlap would indicate that including pain surface provides additional value in pain assessment. In addition to pain intensity and pain surface, pain typology has been recognized as a significant end point for pain assessment [15].

Maxime Billot, Amine Ounajim, Maarten Moens, Lisa Goudman, Jean-Philippe Deneuville, Manuel Roulaud, Kévin Nivole, Mathilde Many, Sandrine Baron, Bertille Lorgeoux, Bénédicte Bouche, Lucie Lampert, Romain David, Philippe Rigoard

J Med Internet Res 2025;27:e62786

Digital, Personalized Clinical Trials Among Older Adults, Lessons Learned From the COVID-19 Pandemic, and Directions for the Future: Aggregated Feasibility Data From Three Trials Among Older Adults

Digital, Personalized Clinical Trials Among Older Adults, Lessons Learned From the COVID-19 Pandemic, and Directions for the Future: Aggregated Feasibility Data From Three Trials Among Older Adults

Despite the presumed barriers to enrolling older adults in digital, remote clinical research, several trials conducted during the COVID-19 pandemic have succeeded in this pursuit, including a longitudinal brain aging study [20], a telemedicine initiative in a primary care setting [21], telehealth delivery of music therapy services [22], and a digital group intervention addressing worry and social isolation [23].

Lindsay Arader, Danielle Miller, Alexandra Perrin, Frank Vicari, Ciaran P Friel, Elizabeth A Vrany, Ashley M Goodwin, Mark Butler

J Med Internet Res 2025;27:e54629

Using Music to Promote Hong Kong Young People’s Emotion Regulation and Reduce Their Mood Symptoms and Loneliness: Protocol for a Pilot Randomized Controlled Trial

Using Music to Promote Hong Kong Young People’s Emotion Regulation and Reduce Their Mood Symptoms and Loneliness: Protocol for a Pilot Randomized Controlled Trial

The proposed pilot trial will evaluate the effectiveness of a music-based prevention program in reducing mood problems among young people by enhancing their emotion regulation skills. This project is supported by a seed grant to conduct a small-scale trial in preparation for future large-scale research.

Yuan Cao, Yuanxin Shi, Debbie Chi Wing Low, Daniel T L Shek, David H K Shum, Radhika Tanksale, Genevieve Dingle

JMIR Res Protoc 2025;14:e67764

A Digital Photo Activity Intervention for Nursing Home Residents With Dementia and Their Carers: Mixed Methods Process Evaluation

A Digital Photo Activity Intervention for Nursing Home Residents With Dementia and Their Carers: Mixed Methods Process Evaluation

Using the app, informal and formal carers can easily conduct the digital photo activity with residents by accessing a database of artistic, black-and-white, generic photos and making a person-centered selection of digital photos to view with the residents [13], as opposed to having a limited collection of printed photos.

Josephine Rose Orejana Tan, David P Neal, Maria Vilmen, Petra Boersma, Teake P Ettema, Robbert J J Gobbens, Sietske A M Sikkes, Rose-Marie Dröes

JMIR Form Res 2025;9:e56586

Acceptability, Usability, and Insights Into Cybersickness Levels of a Novel Virtual Reality Environment for the Evaluation of Depressive Symptoms: Exploratory Observational Study

Acceptability, Usability, and Insights Into Cybersickness Levels of a Novel Virtual Reality Environment for the Evaluation of Depressive Symptoms: Exploratory Observational Study

The VR system was developed using the HP Reverb G2 Omnicept Edition headset, which includes a variety of biometric sensors such as eye tracking, a facial camera (lower), a heart rate sensor, and sensors for brain activity while maintaining the core features of the standard version. These features include a resolution of 2160 × 2160 px per eye, a 114° field of view, a 90 Hz refresh rate, and integrated audio.

Sara Sutori, Emma Therése Eliasson, Francesca Mura, Victor Ortiz, Vincenzo Catrambonephd, Gergö Hadlaczky, Ivo Todorov, Antonio Luca Alfeo, Valentina Cardi, Mario G C A Cimino, Giovanna Mioni, Mariano Alcañiz Raya, Gaetano Valenza, Vladimir Carli, Claudio Gentili

JMIR Form Res 2025;9:e68132

Primary Technology-Enhanced Care for Hypertension Scaling Program: Trial-Based Economic Evaluation Examining Effectiveness and Cost-Effectiveness Using Real-World Data in Singapore

Primary Technology-Enhanced Care for Hypertension Scaling Program: Trial-Based Economic Evaluation Examining Effectiveness and Cost-Effectiveness Using Real-World Data in Singapore

MOHT conducted a pilot trial involving 120 patients from a public primary care clinic in Singapore to evaluate the effectiveness of the PTEC-HT program in a controlled setting adopting a quasi-experimental design. After a follow-up of 6 months, the PTEC-HT program was effective in reducing the BP as well as cost-effective as compared to usual care. Additionally, greater satisfaction was reported for the PTEC-HT group as compared to the usual care group [10].

Yi Wang, Shilpa Tyagi, David Wei Liang Ng, Valerie Hui Ying Teo, David Kok, Dennis Foo, Gerald Choon-Huat Koh

J Med Internet Res 2025;27:e59275

Methadone Patient Access to Collaborative Treatment: Protocol for a Pilot and a Randomized Controlled Trial to Establish Feasibility of Adoption and Impact on Methadone Treatment Delivery and Patient Outcomes

Methadone Patient Access to Collaborative Treatment: Protocol for a Pilot and a Randomized Controlled Trial to Establish Feasibility of Adoption and Impact on Methadone Treatment Delivery and Patient Outcomes

The creation of a trauma-informed codevelopment space was crucial to facilitate safer and more open discussions. To accomplish this, we established a parallel, intervention refinement process using a helical structure developed by this team and based on our prior research with structural indicators for community-based participatory action research [33]. As shown in Figure 2, the “hand off” of work drives an iterative (helical) thinking process.

Beth E Meyerson, Alissa Davis, Richard A Crosby, Linnea B Linde-Krieger, Benjamin R Brady, Gregory A Carter, Arlene N Mahoney, David Frank, Janet Rothers, Zhanette Coffee, Elana Deuble, Jonathon Ebert, Mary F Jablonsky, Marlena Juarez, Barbara Lee, Heather M Lorenz, Michael D Pava, Kristen Tinsely, Sana Yousaf

JMIR Res Protoc 2025;14:e69829

Summarizing Online Patient Conversations Using Generative Language Models: Experimental and Comparative Study

Summarizing Online Patient Conversations Using Generative Language Models: Experimental and Comparative Study

A frequent problem is how to obtain a more qualitative understanding of how the disease affects patients’ daily functioning and living. Most NLP methods, in fact, can extract single entities or concepts from textual data, but there is a lack of methods to analyze textual data at a more qualitative level in terms of the key messages that can be derived from a collection of texts.

Rakhi Asokkumar Subjagouri Nair, Matthias Hartung, Philipp Heinisch, Janik Jaskolski, Cornelius Starke-Knäusel, Susana Veríssimo, David Maria Schmidt, Philipp Cimiano

JMIR Med Inform 2025;13:e62909