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Early Detection of Type 1 Diabetes in First-Degree Relatives in Saudi Arabia (VISION-T1D): Protocol for a Pilot Implementation Study

Early Detection of Type 1 Diabetes in First-Degree Relatives in Saudi Arabia (VISION-T1D): Protocol for a Pilot Implementation Study

Analyses will be conducted by Enable Biosciences, the Barbara Davis Center for Childhood Diabetes, and delegates [28,29]. These tests are used for research purposes only. Testing focuses on identifying high-risk HLA genotypes associated with T1 D, particularly variants in the HLA region (MHC class II alleles), which account for over 50% of T1 D heritability [13].

Iman S Algadi, Yazed AlRuthia, Muhammad H Mujammami, Khaled Hani Aburisheh, Metib Alotaibi, Sharifah Al Issa, Amal A Al-Saif, David Seftel, Cheng-Ting Tsai, Reem A Al Khalifah

JMIR Res Protoc 2025;14:e70575