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Decentralized Biobanking Apps for Patient Tracking of Biospecimen Research: Real-World Usability and Feasibility Study

Decentralized Biobanking Apps for Patient Tracking of Biospecimen Research: Real-World Usability and Feasibility Study

We examined all contexts along the data pipeline, from population-level breast cancer screening to diagnostic biopsies and surgical treatments, clinical pathology, and specimen accessioning through the biobanking platform, where it may be stored for future use in –80 °C freezers or distributed fresh for next-generation biobanking applications such as patient-derived organoids, multi-omics, and high-throughput testing.

William Sanchez, Ananya Dewan, Eve Budd, M Eifler, Robert C Miller, Jeffery Kahn, Mario Macis, Marielle Gross

JMIR Bioinform Biotech 2025;6:e70463

Safety and Efficacy of Modular Digital Psychotherapy for Social Anxiety: Randomized Controlled Trial

Safety and Efficacy of Modular Digital Psychotherapy for Social Anxiety: Randomized Controlled Trial

If the Bayes factor is of ≥3, this indicates evidence for the null hypothesis, whereas a value of b RCT: randomized controlled trial. c BF01: Bayes factor. d BF01 e BF01≥ 3; indicates evidence for the null hypothesis (that both groups were the same). f SPIN: Social Phobia Inventory. g WSAS: Work and Social Adjustment Scale. h GCSE: General Certificate of Secondary Education. i AUDIT-C: Alcohol Use Disorders Identification Test for Consumption. j BF01 between 1 and 3; indicates insufficient evidence for either hypothesis

Mona M Garvert, Jessica McFadyen, Stuart Linke, Tayla McCloud, Sofie S Meyer, Sandra Sobanska, Paul B Sharp, Alex Long, Quentin J M Huys, Mandana Ahmadi

J Med Internet Res 2025;27:e64138

Young Adult Perspectives on Artificial Intelligence–Based Medication Counseling in China: Discrete Choice Experiment

Young Adult Perspectives on Artificial Intelligence–Based Medication Counseling in China: Discrete Choice Experiment

The formula for determining the minimum sample size for a DCE [47] was based on the thumb rule of Johnson and Orme [50]: N≥500 c/ta, where c is the maximum number of levels containing the attribute, t is the number of option sets, and a is the number of options in each option set (including the exit option) [51]. In this experiment, c=5, t=24, and a=3. Calculating the sample size according to the above formula gives a minimum sample size of 312 for this experiment.

Jia Zhang, Jing Wang, JingBo Zhang, XiaoQian Xia, ZiYun Zhou, XiaoMing Zhou, YiBo Wu

J Med Internet Res 2025;27:e67744

Media Framing and Portrayals of Ransomware Impacts on Informatics, Employees, and Patients: Systematic Media Literature Review

Media Framing and Portrayals of Ransomware Impacts on Informatics, Employees, and Patients: Systematic Media Literature Review

Multimedia Appendices 1 and 2 contain the research protocols for PRISMA-S: an extension to the PRISMA statement for reporting literature searches in systematic reviews and standards for reporting qualitative research. On September 15, 2023 we conducted a comprehensive literature search of 3 news databases, from their inception until the date of the search: Access World News, also referred to as News Bank; Newspaper Source; and the Associated Press Newswire.

Atiya Avery, Elizabeth White Baker, Brittany Wright, Ishmael Avery, Dream Gomez

J Med Internet Res 2025;27:e59231

Using Large Language Models to Automate Data Extraction From Surgical Pathology Reports: Retrospective Cohort Study

Using Large Language Models to Automate Data Extraction From Surgical Pathology Reports: Retrospective Cohort Study

(C) Private LLMs: EHR data can be shared with a local hospital LLM, and prompt entry with question curation can be used to gain oncologic insights. EHR: electronic health record. This study was approved by the Institutional Review Board of the Icahn School of Medicine at Mount Sinai (no. 22‐00347). Informed consent was waived given the retrospective nature of the study. To ensure confidentiality of patient data, only authorized research study personnel were permitted access to patient data.

Denise Lee, Akhil Vaid, Kartikeya M Menon, Robert Freeman, David S Matteson, Michael L Marin, Girish N Nadkarni

JMIR Form Res 2025;9:e64544