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Effectiveness of Digital Lifestyle Interventions on Depression, Anxiety, Stress, and Well-Being: Systematic Review and Meta-Analysis

Effectiveness of Digital Lifestyle Interventions on Depression, Anxiety, Stress, and Well-Being: Systematic Review and Meta-Analysis

lifestyle intervention for depressive symptoms and quality of life in individuals with a history of major Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major

Jacinta Brinsley, Edward J O'Connor, Ben Singh, Grace McKeon, Rachel Curtis, Ty Ferguson, Georgia Gosse, Iris Willems, Pieter-Jan Marent, Kimberley Szeto, Joseph Firth, Carol Maher

J Med Internet Res 2025;27:e56975

AI for IMPACTS Framework for Evaluating the Long-Term Real-World Impacts of AI-Powered Clinician Tools: Systematic Review and Narrative Synthesis

AI for IMPACTS Framework for Evaluating the Long-Term Real-World Impacts of AI-Powered Clinician Tools: Systematic Review and Narrative Synthesis

A recent review of 692 FDA-approved AI enabled medical devices highlighted major gaps in transparency and safety reporting [90]. Key data such as ethnicity (reported in only 3.6% of approvals), socioeconomic information (absent in 99.1%), and study participants’ age (missing in 81.6%) were often underreported [90]. In addition, only 46.1% of devices provided detailed performance results and only 1.9% were linked to scientific publications on safety and efficacy [90].

Christine Jacob, Noé Brasier, Emanuele Laurenzi, Sabina Heuss, Stavroula-Georgia Mougiakakou, Arzu Cöltekin, Marc K Peter

J Med Internet Res 2025;27:e67485

Evaluating Reaction Videos of Young People Watching Edutainment Media (MTV Shuga): Qualitative Observational Study

Evaluating Reaction Videos of Young People Watching Edutainment Media (MTV Shuga): Qualitative Observational Study

For group 3, the discussions were also a major component of enjoyment of the show; they stated that they “loved every moment of it because we discussed it afterwards and shed light, so it was very informative.” However, it was not universal that groups enjoyed watching the show in groups—mainly due to discomfort around intimate scenes and relationship dynamics with family members, as referenced in the aforementioned theme.

Venetia Baker, Sarah Mulwa, David Khanyile, Georgia Arnold, Simon Cousens, Cherie Cawood, Isolde Birdthistle

JMIR Form Res 2025;9:e55275

Improving Participant Recruitment in Clinical Trials: Comparative Analysis of Innovative Digital Platforms

Improving Participant Recruitment in Clinical Trials: Comparative Analysis of Innovative Digital Platforms

Despite the performance of clinical trials worldwide, the time-consuming manual process of selecting the participants and matching them to the right study remains a major challenge in the trial recruitment stage [13]. Given the increasing number of accessible clinical trials and the complexity of their designs, the aforementioned processes demand in-depth understanding of patient characteristics and eligibility requirements based on the inclusion criteria [14].

Alexia Georgia Bikou, Elena Deligianni, Foteini Dermiki-Gkana, Nikolaos Liappas, José Gabriel Teriús-Padrón, Maria Eugenia Beltrán Jaunsarás, Maria Fernanda Cabrera-Umpiérrez, Christos Kontogiorgis

J Med Internet Res 2024;26:e60504

Using the Person-Based Approach to Co-Create and Optimize an App-Based Intervention to Support Better Sleep for Adolescents in the United Kingdom: Mixed Methods Study

Using the Person-Based Approach to Co-Create and Optimize an App-Based Intervention to Support Better Sleep for Adolescents in the United Kingdom: Mixed Methods Study

One major limitation is the representativeness of our PPI contributors. Of those invited to share their feedback, only a small proportion volunteered to contribute to co-design. Therefore, it is likely that our contributors were a more highly motivated subsection of our target demographic, and it is possible that their recommendations may not always represent the views of less motivated adolescents.

Sarah E Bennett, Milly H Johnston, Georgia Treneman-Evans, James Denison-Day, Anthony Duffy, Amberly Brigden, Paula Kuberka, Nicholas Christoforou, Lee Ritterband, Jewel Koh, Robert Meadows, Doaa Alamoudi, Ian Nabney, Lucy Yardley

JMIR Hum Factors 2024;11:e63341