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Improving Early Dementia Detection Among Diverse Older Adults With Cognitive Concerns With the 5-Cog Paradigm: Protocol for a Hybrid Effectiveness-Implementation Clinical Trial

Improving Early Dementia Detection Among Diverse Older Adults With Cognitive Concerns With the 5-Cog Paradigm: Protocol for a Hybrid Effectiveness-Implementation Clinical Trial

The study is being carried out at primary care clinics affiliated with 2 large academic health systems: Montefiore Medical Center and Albert Einstein College of Medicine (hereafter referred to as Montefiore-Einstein) in the Bronx, New York, and Indiana University Health (IUH) in Indiana. The Montefiore-Einstein clinics serve an urban population primarily composed of individuals from historically minoritized racial and ethnic groups (Hispanic/Latino and Black populations).

Rachel Beth Rosansky Chalmer, Emmeline Ayers, Erica F Weiss, Nicole R Fowler, Andrew Telzak, Diana Summanwar, Jessica Zwerling, Cuiling Wang, Huiping Xu, Richard J Holden, Kevin Fiori, Dustin D French, Celeste Nsubayi, Asif Ansari, Paul Dexter, Anna Higbie, Pratibha Yadav, James M Walker, Harrshavasan Congivaram, Dristi Adhikari, Mairim Melecio-Vazquez, Malaz Boustani, Joe Verghese

JMIR Res Protoc 2025;14:e60471

Limitations of Binary Classification for Long-Horizon Diagnosis Prediction and Advantages of a Discrete-Time Time-to-Event Approach: Empirical Analysis

Limitations of Binary Classification for Long-Horizon Diagnosis Prediction and Advantages of a Discrete-Time Time-to-Event Approach: Empirical Analysis

Each observation was represented by the triplet {X,T,S}, where X⊆Rd is a d-dimensional feature vector, T∈(0,Emax] is an observed event or censoring time over a finite time horizon, and S∈{0,1} indicates whether T is a right-censoring time (S=0) or an event time (S=1). The observed time T is the minimum of the event time E and the right-censoring time C, that is, T=min(E, C).

De Rong Loh, Elliot D Hill, Nan Liu, Geraldine Dawson, Matthew M Engelhard

JMIR AI 2025;4:e62985