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Skip search results from other journals and go to results- 472 Journal of Medical Internet Research
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Notably, the Kessler-6 primarily focuses on negative affect, anxiety, and depression symptoms rather than other forms of emotional distress (such as anger, which has been linked to suicide risk [64]). Scale items measured the frequency of the following emotions or experiences in the past 30 days: “nervous,” “hopeless,” “restless or fidgety,” “so depressed that nothing could cheer you up,” “that everything was an effort,” and “worthless.”
J Med Internet Res 2025;27:e65452
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Next, for each of the phase 1 and phase 2 groups, paired t tests were conducted to obtain estimates of short-term changes in drinking and attitudinal measures from baseline to follow-up. Box-Cox transformations were performed for the drinking outcomes where there was evidence of nonnormality of data based on skewness (outside of −1 and +1) or kurtosis (outside of −2 and +2) being outside of the conventional acceptable ranges. The pattern of findings did not change when using transformed or raw variables.
JMIR Hum Factors 2025;12:e69873
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Cells in the 5-m L culture tubes will be stimulated with phorbol myristate acetate (Sigma Aldrich) and ionomycin (Sigma Aldrich) in the presence of Golgi Stop (Becton Dickinson) for 4 hours in 37 °C under a 5% CO2 environment to stimulate T-effector cells. Following the incubation periods, the supernatant from cortisol-stimulated cells will be collected and stored at –80 °C until assayed for interleukin (IL)-6, IL-10, IL-8, and IL-4 by using a commercial enzyme-linked immunosorbent assay.
JMIR Res Protoc 2025;14:e66439
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