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Assessing the Noninferiority of a Rhythm and Language Training Serious Game Combined With Speech Therapy Versus Speech Therapy Care for Children With Dyslexia: Protocol for an Investigator-Blinded Randomized Controlled Trial

Assessing the Noninferiority of a Rhythm and Language Training Serious Game Combined With Speech Therapy Versus Speech Therapy Care for Children With Dyslexia: Protocol for an Investigator-Blinded Randomized Controlled Trial

The maximum acceptable inferiority for experimental versus control on the primary outcome is therefore expected to be a standardized difference (Cohen d=0.39), which corresponds to a label between small or medium, depending on the guidelines (R effect size package) [44]. Considering a one-sided significance level of 2.5% and a power of 90%, it is necessary to include 137 participants per group (G*Power 3.1).

Charline Grossard, Mélanie Descamps, Sara Cadoni, Hugues Pellerin, François Vonthron, Jean Xavier, Bruno Falissard, David Cohen

JMIR Res Protoc 2025;14:e71326

GPT-4 as a Clinical Decision Support Tool in Ischemic Stroke Management: Evaluation Study

GPT-4 as a Clinical Decision Support Tool in Ischemic Stroke Management: Evaluation Study

Agreement between treatment decisions was measured using a linear weighted Cohen κ coefficient, using the psych 2.3.12 library. This study was approved by the Rambam Medical Center Helsinki Committee (0156-24-D) as a retrospective analysis. The requirement for informed consent was waived due to the retrospective nature of the study and the use of deidentified data. All patient information was anonymized prior to analysis, with all identifiers, names, and dates removed to ensure privacy and confidentiality.

Amit Haim Shmilovitch, Mark Katson, Michal Cohen-Shelly, Shlomi Peretz, Dvir Aran, Shahar Shelly

JMIR AI 2025;4:e60391

A Self-Adaptive Serious Game to Improve Motor Learning Among Older Adults in Immersive Virtual Reality: Short-Term Longitudinal Pre-Post Study on Retention and Transfer

A Self-Adaptive Serious Game to Improve Motor Learning Among Older Adults in Immersive Virtual Reality: Short-Term Longitudinal Pre-Post Study on Retention and Transfer

The effect size was computed using η² for ANOVAs, ε² for the Friedman test, and adjusted Cohen d for parametric post-hoc pairwise comparisons and 2-tailed t tests. For nonparametric tests, Cohen r was used. η² for ANOVAs and ε² for the Friedman test provide an estimate of the effect's magnitude relative to the total variance, with values of 0.01, 0.06, and 0.14 indicating small, medium, and large effects, respectively.

Gauthier Everard, Louise Declerck, Thierry Lejeune, Martin Gareth Edwards, Justine Bogacki, Cléo Reiprich, Kelly Delvigne, Nicolas Legrain, Charles Sebiyo Batcho

JMIR Aging 2025;8:e64004