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Early In-Bed Cycle Ergometry With Critically Ill, Mechanically Ventilated Patients: Statistical Analysis Plan for CYCLE (Critical Care Cycling to Improve Lower Extremity Strength), an International, Multicenter, Randomized Clinical Trial

Early In-Bed Cycle Ergometry With Critically Ill, Mechanically Ventilated Patients: Statistical Analysis Plan for CYCLE (Critical Care Cycling to Improve Lower Extremity Strength), an International, Multicenter, Randomized Clinical Trial

Diane Heels-Ansdell, Laurel Kelly, Heather K O'Grady, Christopher Farley, Julie C Reid, Sue Berney, Amy M Pastva, Karen EA Burns, Frédérick D'Aragon, Margaret S Herridge, Andrew Seely, Jill Rudkowski, Bram Rochwerg, Alison Fox-Robichaud, Ian Ball, Francois Lamontagne, Erick H Duan, Jennifer Tsang, Patrick M Archambault, Avelino C Verceles, John Muscedere, Sangeeta Mehta, Shane W English, Tim Karachi, Karim Serri, Brenda Reeve, Lehana Thabane, Deborah Cook, Michelle E Kho

JMIR Res Protoc 2024;13:e54451

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Trust but Verify: Lessons Learned for the Application of AI to Case-Based Clinical Decision-Making From Postmarketing Drug Safety Assessment at the US Food and Drug Administration

Trust but Verify: Lessons Learned for the Application of AI to Case-Based Clinical Decision-Making From Postmarketing Drug Safety Assessment at the US Food and Drug Administration

Figure 1 provides an overview of the ICSR evaluation workflow (Figure 1 is adapted from the study by Ball and Dal Pan [8]. Case definitions are a set of prespecified criteria for determining whether a patient should be identified as having a particular disease, injury, or other health condition (ie, AE) [2]).

Robert Ball, Andrew H Talal, Oanh Dang, Monica Muñoz, Marianthi Markatou

J Med Internet Res 2024;26:e50274

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Development of a Digital Health Intervention to Support Patients on a Waitlist for Orthopedic Specialist Care: Co-Design Study

Development of a Digital Health Intervention to Support Patients on a Waitlist for Orthopedic Specialist Care: Co-Design Study

Alexander Tacey, Jack Behne, Rhiannon K Patten, Minh Truc Ngo, Rees Thomas, Jessica Ancilleri, Chelsea Bone, Angela Paredes Castro, Helen McCarthy, Katherine Harkin, Julia FM Gilmartin-Thomas, Amir Takla, Calum Downie, Jane Mulcahy, Michelle Ball, Jenny Sharples, Sarah Dash, Amy Lawton, Breanna Wright, Peter Sleeth, Tina Kostecki, Christopher Sonn, Michael J McKenna, Vasso Apostolopoulos, Rebecca Lane, Catherine M Said, Mary De Gori, Andrew McAinch, Phong Tran, Itamar Levinger, Alexandra Parker, Mary N Woessner, Michaela Pascoe

JMIR Form Res 2023;7:e41974

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