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The PMIS (Pearson r=−0.76; P
As we examined the sensitivity and specificity data to choose cut scores, we chose to favor sensitivity to minimize missing individuals with true disease in this sample of patients considered high risk because of their cognitive concerns. The cut scores for a positive result on the 5-Cog components were as follows: PMIS ≤6 (range 0-8), Symbol Match ≤25 (range 0-65), and s MCR >5 (range 0-7).
JMIR Res Protoc 2025;14:e60471
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The application of this mapping to the data was performed using R version 4.3.2 (R Foundation for Statistical Computing). The full list of diagnosis names corresponding to ADRD diagnosis categories is provided in Multimedia Appendix 1.
To assess associations between clusters and sex, as well as ADRD diagnoses, we used the chi-square test.
JMIR Aging 2025;8:e65178
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Reverse scored features have an R suffix, for example, Sias5 R.
PDSS question standardised coefficients. This chart illustrates the relative importance of the PDSS questions with respect to the pseudo-sum score for the PDSS (pdss) after model training.
Fear Questionnaire (FQ) anxiety depression subscale question standardized coefficients. This chart illustrates the relative importance of the Fear Questionnaire Total Phobia Score questions with respect to the pseudosum score (fq) after model training.
JMIR Med Inform 2025;13:e64617
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