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Maternal Metabolic Health and Mother and Baby Health Outcomes (MAMBO): Protocol of a Prospective Observational Study

Maternal Metabolic Health and Mother and Baby Health Outcomes (MAMBO): Protocol of a Prospective Observational Study

Summary of study activities. a Hb A1c: hemoglobin A1c. b CRP: C-reactive protein. c OGTT: oral glucose tolerance test. At the first visit, a full medical history will be taken by a trained clinician including past medical history and surgical history. Outcomes of previous pregnancies will be recorded including outcome of the pregnancy, gestation, pregnancy complications, and (if relevant) birthweight and neonatal complications. Current medications including dose, and dosing schedule will be recorded.

Sarah A L Price, Digsu N Koye, Alice Lewin, Alison Nankervis, Stefan C Kane

JMIR Res Protoc 2025;14:e72542

Effects of Using a Smart Bassinet on the Mental Health of Military-Affiliated Pregnant Women: Protocol for a Randomized Controlled Sleep Health and Mood in Newly Expectant Military Mothers (SHINE) Trial

Effects of Using a Smart Bassinet on the Mental Health of Military-Affiliated Pregnant Women: Protocol for a Randomized Controlled Sleep Health and Mood in Newly Expectant Military Mothers (SHINE) Trial

PBMCs will be frozen and stored at –80 °C using 10% dimethylsulfoxide, thereby allowing all samples to be analyzed in parallel. Plasma will also be stored at –80 °C. In our prior studies, we have missing biological data (due to incomplete blood draws) in about 7% of the visits; we anticipate similar rates in this study. Cytokine analysis will be performed under Dr Osborne’s supervision in the PIPPI laboratory at Weill Cornell Medicine.

Michele L Okun, Jennifer L Payne, Lauren M Osborne, Leilani Feliciano, Andrew Lac

JMIR Res Protoc 2025;14:e66439

Decentralized Biobanking Apps for Patient Tracking of Biospecimen Research: Real-World Usability and Feasibility Study

Decentralized Biobanking Apps for Patient Tracking of Biospecimen Research: Real-World Usability and Feasibility Study

We examined all contexts along the data pipeline, from population-level breast cancer screening to diagnostic biopsies and surgical treatments, clinical pathology, and specimen accessioning through the biobanking platform, where it may be stored for future use in –80 °C freezers or distributed fresh for next-generation biobanking applications such as patient-derived organoids, multi-omics, and high-throughput testing.

William Sanchez, Ananya Dewan, Eve Budd, M Eifler, Robert C Miller, Jeffery Kahn, Mario Macis, Marielle Gross

JMIR Bioinform Biotech 2025;6:e70463