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Maternal Metabolic Health and Mother and Baby Health Outcomes (MAMBO): Protocol of a Prospective Observational Study

Maternal Metabolic Health and Mother and Baby Health Outcomes (MAMBO): Protocol of a Prospective Observational Study

Summary of study activities. a Hb A1c: hemoglobin A1c. b CRP: C-reactive protein. c OGTT: oral glucose tolerance test. At the first visit, a full medical history will be taken by a trained clinician including past medical history and surgical history. Outcomes of previous pregnancies will be recorded including outcome of the pregnancy, gestation, pregnancy complications, and (if relevant) birthweight and neonatal complications. Current medications including dose, and dosing schedule will be recorded.

Sarah A L Price, Digsu N Koye, Alice Lewin, Alison Nankervis, Stefan C Kane

JMIR Res Protoc 2025;14:e72542

Comparison of Deep Learning Approaches Using Chest Radiographs for Predicting Clinical Deterioration: Retrospective Observational Study

Comparison of Deep Learning Approaches Using Chest Radiographs for Predicting Clinical Deterioration: Retrospective Observational Study

Model performance area under the receiver operating characteristic curve (AUROC) with the validation dataset across different model architectures, pretrained weights, and image augmentation methods. a The average AUROC score is for a particular model over different augmentation methods b The “Average score over models” row presents the average AUROC score of a particular augmentation method over different models. c"—” indicates not applicable. d The “Average improvement” row shows the average AUROC improvement

Mahmudur Rahman, Jifan Gao, Kyle A Carey, Dana P Edelson, Askar Afshar, John W Garrett, Guanhua Chen, Majid Afshar, Matthew M Churpek

JMIR AI 2025;4:e67144

Effects of Using a Smart Bassinet on the Mental Health of Military-Affiliated Pregnant Women: Protocol for a Randomized Controlled Sleep Health and Mood in Newly Expectant Military Mothers (SHINE) Trial

Effects of Using a Smart Bassinet on the Mental Health of Military-Affiliated Pregnant Women: Protocol for a Randomized Controlled Sleep Health and Mood in Newly Expectant Military Mothers (SHINE) Trial

PBMCs will be frozen and stored at –80 °C using 10% dimethylsulfoxide, thereby allowing all samples to be analyzed in parallel. Plasma will also be stored at –80 °C. In our prior studies, we have missing biological data (due to incomplete blood draws) in about 7% of the visits; we anticipate similar rates in this study. Cytokine analysis will be performed under Dr Osborne’s supervision in the PIPPI laboratory at Weill Cornell Medicine.

Michele L Okun, Jennifer L Payne, Lauren M Osborne, Leilani Feliciano, Andrew Lac

JMIR Res Protoc 2025;14:e66439

Association of Social Media Recruitment and Depression Among Racially and Ethnically Diverse Metabolic and Bariatric Surgery Candidates: Prospective Cohort Study

Association of Social Media Recruitment and Depression Among Racially and Ethnically Diverse Metabolic and Bariatric Surgery Candidates: Prospective Cohort Study

A 2014 meta-analysis of 164 studies involving 160,000 patients found that BMI decreased by at least 11.8 kg/m² one-year post MBS, with sustained weight loss observed five years post surgery [5]. Most individuals who undergo MBS experience a reduction or complete elimination of obesity-related health issues, including high blood pressure, heart disease, diabetes, asthma, and osteoarthritis [6,7].

Jackson M Francis, Sitapriya S Neti, Dhatri Polavarapu, Folefac Atem, Luyu Xie, Olivia Kapera, Matthew S Mathew, Elisa Marroquin, Carrie McAdams, Jeffrey Schellinger, Sophia Ngenge, Sachin Kukreja, Benjamin E Schneider, Jaime P Almandoz, Sarah E Messiah

JMIR Form Res 2025;9:e58916

Decentralized Biobanking Apps for Patient Tracking of Biospecimen Research: Real-World Usability and Feasibility Study

Decentralized Biobanking Apps for Patient Tracking of Biospecimen Research: Real-World Usability and Feasibility Study

We examined all contexts along the data pipeline, from population-level breast cancer screening to diagnostic biopsies and surgical treatments, clinical pathology, and specimen accessioning through the biobanking platform, where it may be stored for future use in –80 °C freezers or distributed fresh for next-generation biobanking applications such as patient-derived organoids, multi-omics, and high-throughput testing.

William Sanchez, Ananya Dewan, Eve Budd, M Eifler, Robert C Miller, Jeffery Kahn, Mario Macis, Marielle Gross

JMIR Bioinform Biotech 2025;6:e70463

Safety and Efficacy of Modular Digital Psychotherapy for Social Anxiety: Randomized Controlled Trial

Safety and Efficacy of Modular Digital Psychotherapy for Social Anxiety: Randomized Controlled Trial

If the Bayes factor is of ≥3, this indicates evidence for the null hypothesis, whereas a value of b RCT: randomized controlled trial. c BF01: Bayes factor. d BF01 e BF01≥ 3; indicates evidence for the null hypothesis (that both groups were the same). f SPIN: Social Phobia Inventory. g WSAS: Work and Social Adjustment Scale. h GCSE: General Certificate of Secondary Education. i AUDIT-C: Alcohol Use Disorders Identification Test for Consumption. j BF01 between 1 and 3; indicates insufficient evidence for either hypothesis

Mona M Garvert, Jessica McFadyen, Stuart Linke, Tayla McCloud, Sofie S Meyer, Sandra Sobanska, Paul B Sharp, Alex Long, Quentin J M Huys, Mandana Ahmadi

J Med Internet Res 2025;27:e64138