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Limitations of Binary Classification for Long-Horizon Diagnosis Prediction and Advantages of a Discrete-Time Time-to-Event Approach: Empirical Analysis

Limitations of Binary Classification for Long-Horizon Diagnosis Prediction and Advantages of a Discrete-Time Time-to-Event Approach: Empirical Analysis

Each observation was represented by the triplet {X,T,S}, where X⊆Rd is a d-dimensional feature vector, T∈(0,Emax] is an observed event or censoring time over a finite time horizon, and S∈{0,1} indicates whether T is a right-censoring time (S=0) or an event time (S=1). The observed time T is the minimum of the event time E and the right-censoring time C, that is, T=min(E, C).

De Rong Loh, Elliot D Hill, Nan Liu, Geraldine Dawson, Matthew M Engelhard

JMIR AI 2025;4:e62985

Theory-Based Social Media Intervention for Nonmedical Use of Prescription Opioids in Young Adults: Protocol for a Randomized Controlled Trial

Theory-Based Social Media Intervention for Nonmedical Use of Prescription Opioids in Young Adults: Protocol for a Randomized Controlled Trial

In terms of the aim for the preliminary efficacy evaluation (ie, secondary outcomes of psychosocial and behavioral factors associated with NMUPO), we estimate an effect size according to a previous review on digital interventions for illicit drug use [111] and found small-to-medium effect sizes (Cohen d=–0.17 to –0.34) with a 6-month follow-up assessment. G-power analysis [112] estimated a sample size of 10 to 35 per arm for an RCT (repeated measures analysis of covariance).

Cheuk Chi Tam, Sean D Young, Sayward Harrison, Xiaoming Li, Alain H Litwin

JMIR Res Protoc 2025;14:e65847

Treatment of Substance Use Disorders With a Mobile Phone App Within Rural Collaborative Care Management (Senyo Health): Protocol for a Mixed Methods Randomized Controlled Trial

Treatment of Substance Use Disorders With a Mobile Phone App Within Rural Collaborative Care Management (Senyo Health): Protocol for a Mixed Methods Randomized Controlled Trial

Panel (C) shows a behavioral activation task, and panel (D) showcases the points awarded for completing this task. Senyo Health chat feature being displayed from the perspective of the recovery coach. The left is conversations with multiple patients. Once selected, the full conversation appears in the center of the screen, with the recovery coach able to text back and forth. Surveys, modules, and activation tasks can also be assigned to the participant through the chat.

Tyler S Oesterle, Nicholas L Bormann, Margaret M Paul, Scott A Breitinger, Benjamin Lai, Jamie L Smith, Cindy J Stoppel, Stephan Arndt, Mark D Williams

JMIR Res Protoc 2025;14:e65693

Dying in Darkness: Deviations From Data Sharing Ethics in the US Public Health System and the Data Genocide of American Indian and Alaska Native Communities

Dying in Darkness: Deviations From Data Sharing Ethics in the US Public Health System and the Data Genocide of American Indian and Alaska Native Communities

For example, Megan Doerr argues that building or establishing a “social license” for collecting and using data can be more appropriate and protective than deidentification [47]. A social license represents the informal permission of a community to engage in a specific activity [48,49]. In public health contexts, a social license can legitimize the collection, use, or sharing of data about relevant communities.

Cason D Schmit, Meghan Curry O’Connell, Sarah Shewbrooks, Charles Abourezk, Fallon J Cochlin, Megan Doerr, Hye-Chung Kum

J Med Internet Res 2025;27:e70983