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Detecting Sleep/Wake Rhythm Disruption Related to Cognition in Older Adults With and Without Mild Cognitive Impairment Using the myRhythmWatch Platform: Feasibility and Correlation Study

Detecting Sleep/Wake Rhythm Disruption Related to Cognition in Older Adults With and Without Mild Cognitive Impairment Using the myRhythmWatch Platform: Feasibility and Correlation Study

From the extended-cosine models, we extracted measures of 24-hour robustness (pseudo-F statistic, indicating how well the observed data fits the 24-hour curve); activity onset time (up-mesor, the time which the modeled activity level passes the middle modeled rhythm height prior to the peak); and activity offset time (down-mesor or the time which the modeled activity level passes the middle modeled rhythm height prior to the nadir).

Caleb D Jones, Rachel Wasilko, Gehui Zhang, Katie L Stone, Swathi Gujral, Juleen Rodakowski, Stephen F Smagula

JMIR Aging 2025;8:e67294

Anticipated Acceptability of Blended Learning Among Lay Health Care Workers in Malawi: Qualitative Analysis Guided by the Technology Acceptance Model

Anticipated Acceptability of Blended Learning Among Lay Health Care Workers in Malawi: Qualitative Analysis Guided by the Technology Acceptance Model

Ethical clearance was provided by the University of North Carolina at Chapel Hill institutional review board (#20‐1810), the Malawi National Health Sciences Research Committee (#20/06/2566) and the Baylor College of Medicine institutional review board (H-48800). Interviewers obtained written informed consent from all participants before starting the IDIs, reminding participants that their participation was voluntary and could be withdrawn at any time.

Tiwonge E Mbeya-Munkhondya, Caroline J Meek, Mtisunge Mphande, Tapiwa A Tembo, Mike J Chitani, Milenka Jean-Baptiste, Caroline Kumbuyo, Dhrutika Vansia, Katherine R Simon, Sarah E Rutstein, Victor Mwapasa, Vivian Go, Maria H Kim, Nora E Rosenberg

JMIR Form Res 2025;9:e62741

Improving Early Dementia Detection Among Diverse Older Adults With Cognitive Concerns With the 5-Cog Paradigm: Protocol for a Hybrid Effectiveness-Implementation Clinical Trial

Improving Early Dementia Detection Among Diverse Older Adults With Cognitive Concerns With the 5-Cog Paradigm: Protocol for a Hybrid Effectiveness-Implementation Clinical Trial

Preliminary results suggest that the 5-Cog paradigm is a cost-effective option compared to “enhanced usual care” for the early detection of cognitive impairment in primary care (H Congivaram, BS, unpublished data, December 2024). Investigators have begun collecting cost estimates for 5-Cog procedures and resulting health care costs in the IUH system, as these were not previously collected.

Rachel Beth Rosansky Chalmer, Emmeline Ayers, Erica F Weiss, Nicole R Fowler, Andrew Telzak, Diana Summanwar, Jessica Zwerling, Cuiling Wang, Huiping Xu, Richard J Holden, Kevin Fiori, Dustin D French, Celeste Nsubayi, Asif Ansari, Paul Dexter, Anna Higbie, Pratibha Yadav, James M Walker, Harrshavasan Congivaram, Dristi Adhikari, Mairim Melecio-Vazquez, Malaz Boustani, Joe Verghese

JMIR Res Protoc 2025;14:e60471