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MARIA (Medical Assistance and Rehabilitation Intelligent Agent) for Medication Adherence in Patients With Heart Failure: Empirical Results From a Wizard of Oz Systematic Conversational Agent Design Clinical Protocol

MARIA (Medical Assistance and Rehabilitation Intelligent Agent) for Medication Adherence in Patients With Heart Failure: Empirical Results From a Wizard of Oz Systematic Conversational Agent Design Clinical Protocol

However, no study has specifically displayed a method for building agents’ natural language–based conversations to encourage and educate patients with HF about medication adherence, nor a standard for evaluating this type of CA design early in the development stage as a DH solution. Therefore, our study aims to adopt established design methods and conceive them into a systematic method that uses a clinical observational study protocol.

Nik Nailah Abdullah, Jia Tang, Hemad Fetrati, Nor Fadhilah Binti Kaukiah, Sahrin Bin Saharudin, Vee Sim Yong, Chia How Yen

JMIR Cardio 2025;9:e55846