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Maternal Metabolic Health and Mother and Baby Health Outcomes (MAMBO): Protocol of a Prospective Observational Study

Maternal Metabolic Health and Mother and Baby Health Outcomes (MAMBO): Protocol of a Prospective Observational Study

Summary of study activities. a Hb A1c: hemoglobin A1c. b CRP: C-reactive protein. c OGTT: oral glucose tolerance test. At the first visit, a full medical history will be taken by a trained clinician including past medical history and surgical history. Outcomes of previous pregnancies will be recorded including outcome of the pregnancy, gestation, pregnancy complications, and (if relevant) birthweight and neonatal complications. Current medications including dose, and dosing schedule will be recorded.

Sarah A L Price, Digsu N Koye, Alice Lewin, Alison Nankervis, Stefan C Kane

JMIR Res Protoc 2025;14:e72542

Comparison of Deep Learning Approaches Using Chest Radiographs for Predicting Clinical Deterioration: Retrospective Observational Study

Comparison of Deep Learning Approaches Using Chest Radiographs for Predicting Clinical Deterioration: Retrospective Observational Study

Model performance area under the receiver operating characteristic curve (AUROC) with the validation dataset across different model architectures, pretrained weights, and image augmentation methods. a The average AUROC score is for a particular model over different augmentation methods b The “Average score over models” row presents the average AUROC score of a particular augmentation method over different models. c"—” indicates not applicable. d The “Average improvement” row shows the average AUROC improvement

Mahmudur Rahman, Jifan Gao, Kyle A Carey, Dana P Edelson, Askar Afshar, John W Garrett, Guanhua Chen, Majid Afshar, Matthew M Churpek

JMIR AI 2025;4:e67144

Decentralized Biobanking Apps for Patient Tracking of Biospecimen Research: Real-World Usability and Feasibility Study

Decentralized Biobanking Apps for Patient Tracking of Biospecimen Research: Real-World Usability and Feasibility Study

We examined all contexts along the data pipeline, from population-level breast cancer screening to diagnostic biopsies and surgical treatments, clinical pathology, and specimen accessioning through the biobanking platform, where it may be stored for future use in –80 °C freezers or distributed fresh for next-generation biobanking applications such as patient-derived organoids, multi-omics, and high-throughput testing.

William Sanchez, Ananya Dewan, Eve Budd, M Eifler, Robert C Miller, Jeffery Kahn, Mario Macis, Marielle Gross

JMIR Bioinform Biotech 2025;6:e70463