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In addition, noninferiority in word reading skills (speed and accuracy) and meta-phonological skills will be assessed using respectively the Alouette-R [38] text reading test and the BALE Phoneme Suppression Test [39].
The impact of Poppins Clinical on parents’ stress levels and quality of life will be measured using the Parenting Stress Index-Short Form (PSI-SF) and the EQ-5 D-5 L [40] quality of life questionnaire.
JMIR Res Protoc 2025;14:e71326
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The PMIS (Pearson r=−0.76; P
As we examined the sensitivity and specificity data to choose cut scores, we chose to favor sensitivity to minimize missing individuals with true disease in this sample of patients considered high risk because of their cognitive concerns. The cut scores for a positive result on the 5-Cog components were as follows: PMIS ≤6 (range 0-8), Symbol Match ≤25 (range 0-65), and s MCR >5 (range 0-7).
JMIR Res Protoc 2025;14:e60471
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Statistical analyses were conducted using SAS (SAS Institute) [46] and R software (R Foundation for Statistical Computing) [47], and significance was determined at a P value of .05.
Following transcription, 3 members of the research team (SS, SM, and TC) conducted a double-coding process on the transcripts from 52% (12/23) intervention group participants and 48% (11/23) control group participants.
JMIR Form Res 2025;9:e67997
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All statistical analyses were performed using R (version 4.3.1; R Core Team) [62] and RStudio (version 2023.06.1; RStudio Inc) [64].
The sociodemographic characteristics of the participants are presented in Table 1. All groups’ median years of education were more than 11 years, indicating that at least half of the participants had finished secondary school.
JMIR Serious Games 2025;13:e66167
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