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Approach to Design and Evaluate Digital Tools to Enhance Young Adult Participation in Clinical Trials: Co-Design and Controlled Intercept Study

Approach to Design and Evaluate Digital Tools to Enhance Young Adult Participation in Clinical Trials: Co-Design and Controlled Intercept Study

COVID-19 vaccine–related keywords “COVID-19 vaccine”, “COVID 19 vaccine”, “SARS-Co V2 vaccine”, “Coronavirus disease 2019 vaccine”, “m RNA-1273”, “Pfizer; Bio NTech”, “BNT162”, “Moderna”, “J&J” “Johnson & Johnson” Clinical trial–related keywords “Clinical trial”, “trial” Adapted inductive content coding approach of objective and subjective factors for clinical trial participation used in social listening analysis on Quora.

Tim Mackey, Raphael E Cuomo, Qing Xu, Tiana J McMann, Zhuoran Li, Mingxiang Cai, Christine Wenzel, Joshua S Yang

J Med Internet Res 2025;27:e70852

Support of Home-Based Structured Walking Training and Prediction of the 6-Minute Walk Test Distance in Patients With Peripheral Arterial Disease Based on Telehealth Data: Prospective Cohort Study

Support of Home-Based Structured Walking Training and Prediction of the 6-Minute Walk Test Distance in Patients With Peripheral Arterial Disease Based on Telehealth Data: Prospective Cohort Study

Logarithmic interpolation was used to fit a logarithmic function as defined by the parameters an,i and bn,i into all measured 6 MWT distances dk,j performed at week xk,j until week n by the respective patient i. The estimated distance at the study end as derived in week n for patient i (dlog_ind,n,i) was calculated according to equation 2. Assuming that all patients improved similarly, logarithmic interpolation was also applied to data from all patients when defining parameters an and bn in week n.

Fabian Wiesmüller, Andreas Prenner, Andreas Ziegl, Gihan El-Moazen, Robert Modre-Osprian, Martin Baumgartner, Marianne Brodmann, Gerald Seinost, Günther Silbernagel, Günter Schreier, Dieter Hayn

JMIR Form Res 2025;9:e65721