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Cooperative Virtual Reality Gaming for Anxiety and Pain Reduction in Pediatric Patients and Their Caregivers During Painful Medical Procedures: Protocol for a Randomized Controlled Trial

Cooperative Virtual Reality Gaming for Anxiety and Pain Reduction in Pediatric Patients and Their Caregivers During Painful Medical Procedures: Protocol for a Randomized Controlled Trial

Liszio et al [28] have shown that the audiovisual presentation of virtual underwater environments significantly reduces acute and anticipatory stress. However, research on the effect of solely auditive presentation of nature sounds on the emotional experience of patients in medical situations is scarce; however, there is some evidence in the literature.

Stefan Liszio, Franziska Bäuerlein, Jens Hildebrand, Carolin van Nahl, Maic Masuch, Oliver Basu

JMIR Res Protoc 2025;14:e63098