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Moreover, we wanted to include the ethics of the consortium (eg, ensuring psychological safety in research teams) rather than merely looking at the ethics in the consortium (eg, avoiding biased outcomes of the prognostic models).
Therefore, we opted for an embedded review, which, in the typology of Mc Dougall [8], could be best described as a critical interpretative review, with the main difference that we established the analytical categories together with the researchers of the consortium.
JMIR Cancer 2025;11:e65566
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Although AI-driven tools have already shown promise in improving diagnosis, triage, and decision-making in emergency department settings [4], in the context of prehospital emergency response, most research has remained at the proof-of-concept stage, highlighting the need for prospective validation to support real-world implementation [6].
J Med Internet Res 2025;27:e67318
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After deciding on the topic of research, we identified the steps to be taken for the literature review as follows:
Search criteria
Literature assembly
Study selection
Research questions
Inclusion and exclusion criteria
Full-text paper assessment
Numerous studies have conducted literature reviews to assess the use of machine learning for disease prediction.
JMIR AI 2025;4:e59094
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The Robert Koch Institute (RKI), a federal agency and research institute responsible for disease control and prevention in Germany, has recognized the practical benefits of this approach. At the RKI, an ED syndromic surveillance system has been established in 2020, using daily routine data from the German Emergency Department Data Registry AKTIN [2]. Currently, 58 EDs in 12 German federal states voluntarily provide data for research and surveillance purposes.
JMIR Public Health Surveill 2025;11:e66218
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Women with lower urinary tract symptoms (LUTS) report more frequently engaging in toileting behaviors such as hovering to urinate, delayed toileting or holding, and straining during toileting [1-5]. However, whether these examples of toileting behaviors contribute to LUTS, represent adaptations to the presence of symptoms, or a complex interaction between environmental, sociocultural, and physiological factors is unclear.
JMIR Mhealth Uhealth 2025;13:e56533
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Indeed, a lack of generalizability was a limitation highlighted in previous studies with small samples (eg, N=168 [4] and N=37 [16]) recruited from specific regions [4,8-11,14,15,19]. Similarly, qualitative research draws on the experiences and beliefs of small, selective samples and can rarely be considered to provide generalizable conclusions (although generalizability is not the primary aim of such research) [20].
J Med Internet Res 2025;27:e63634
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However, a study in the United Kingdom showed that adding an SMS reminder to the standard letter reminder resulted in an increase in participation only among first-time invitees [11]. In addition, a systematic review of SMS text message interventions for cancer screening found that they had a small effect on CRC screening rates, ranging from 0.6% to 3.3% [12]. There is, therefore, a need for further research to explore the potential of this approach more comprehensively.
JMIR Mhealth Uhealth 2025;13:e64243
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We used the following measures to evaluate changes in participants’ mental health:
Depressive symptoms were measured by the Patient Health Questionnaire Adolescent version (PHQ-A). The PHQ-A is a well-established measure to assess depressive symptoms over the preceding 2 weeks [30]. The PHQ-A total score ranges from 0 to 27.
JMIR Serious Games 2024;12:e59381
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Aligned with this, a project was undertaken in 2019 to promote and update an existing policy prohibiting all forms of tobacco on campus, while also enhancing the availability of cessation support programs [42,43]. Additionally, contextual research was conducted to assess the educational needs and well-being of students during the COVID-19 pandemic [44-46].
JMIR Res Protoc 2024;13:e58860
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The rapidly changing nature of social media related behaviors exacerbates the difficulty of inquiry in this field and necessitates focused social media research questions to try to extend and explain the findings from existing studies to explore this complexity in greater depth.
J Med Internet Res 2024;26:e57154
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