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Web-Based Explainable Machine Learning-Based Drug Surveillance for Predicting Sunitinib- and Sorafenib-Associated Thyroid Dysfunction: Model Development and Validation Study

Web-Based Explainable Machine Learning-Based Drug Surveillance for Predicting Sunitinib- and Sorafenib-Associated Thyroid Dysfunction: Model Development and Validation Study

This retrospective study used the deidentified Clinical Research Database (CRD) which includes data from Taipei Medical University Hospital, Wan Fang Hospital, and Shuang Ho Hospital of the TMU health care system. Ethical review for this study was waived by the TMU-Joint Institutional Review Board (approval no.: N202202053). As the data had been deidentified, the requirement for informed consent was waived. No compensation was provided to the participants.

Fan-Ying Chan, Yi-En Ku, Wen-Nung Lie, Hsiang-Yin Chen

JMIR Form Res 2025;9:e67767