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Community Versus Facility-Based Services to Improve the Screening of Active Hepatitis C Virus Infection in Cambodia: The ANRS 12384 CAM-C Cluster Randomized Controlled Trial—Protocol for a Mixed Methods Study

Community Versus Facility-Based Services to Improve the Screening of Active Hepatitis C Virus Infection in Cambodia: The ANRS 12384 CAM-C Cluster Randomized Controlled Trial—Protocol for a Mixed Methods Study

This study also identified two significant risk factors for HCV infection: having a family member positive for HCV and the use of intravenous medication in the past 5 years [10]. These efforts underscore the complexity of the hepatitis epidemic in Cambodia and the multifaceted approach required to address it.

Emilie Mosnier, Olivier Ségéral, Sansothy Neth, Luis Sagaon-Teyssier, Dyna Khuon, Chan Leakhena Phoeung, Sovatha Mam, Chhingsrean Chhay, Kimeang Heang, Jean Charles Duclos-Vallée, Vonthanak Saphonn

JMIR Res Protoc 2024;13:e63376

Understanding Users’ Engagement in a Provider-Created Mobile App for Training to Advance Hepatitis C Care: Knowledge Assessment Survey Study

Understanding Users’ Engagement in a Provider-Created Mobile App for Training to Advance Hepatitis C Care: Knowledge Assessment Survey Study

Existing literature available for HCV education is focused on the comanagement of opioid use disorders and do not provide targeted information on general HCV treatment and cure [17-19]. In response to these gaps as well as needs assessment and feedback from multidisciplinary stakeholders, we developed an app to address the lack of HCV educational resources available to patients and health care supportive staff. The app guides the user through the HCV treatment stages in a self-exploratory way.

Maximilian Wegener, Katarzyna Sims, Ralph Brooks, Lisa Nichols, Robert Sideleau, Sharen McKay, Merceditas Villanueva

JMIR Form Res 2024;8:e52729

Care Integration for Hepatitis C Virus Treatment Through Facilitated Telemedicine Within Opioid Treatment Programs: Qualitative Study

Care Integration for Hepatitis C Virus Treatment Through Facilitated Telemedicine Within Opioid Treatment Programs: Qualitative Study

Additionally, people with OUD have high hepatitis C virus (HCV) incidence and prevalence due to injection drug use and limited access to HCV therapy [3]. To achieve HCV elimination by 2030, as proposed in several jurisdictions [4-6], HCV treatment access must increase. We sought to address restricted HCV care access for people with OUD through a randomized controlled trial of care integration using technology that is at the intersection of the internet or videoconferencing, and health care.

Suzanne S Dickerson, Saliyah J George, Ana Ventuneac, Arpan Dharia, Andrew H Talal

J Med Internet Res 2024;26:e53049

Characteristics of Hepatitis B Virus, Hepatitis C Virus, and Syphilis Coinfection in People With HIV/AIDS Contracted Through Different Sources: Retrospective Study

Characteristics of Hepatitis B Virus, Hepatitis C Virus, and Syphilis Coinfection in People With HIV/AIDS Contracted Through Different Sources: Retrospective Study

Hepatitis B virus (HBV), hepatitis C virus (HCV), and syphilis infection are also all major public health problems worldwide. HBV, HCV, and syphilis are the 3 most common infections among people living with HIV/AIDS all over the world and share similar transmission routes [2,3]. The burden of HBV, HCV, and syphilis infection in people living with HIV/AIDS is even larger than in the general population. The ever-increasing burden of these infections has become a growing concern [4].

Rongrong Yang, Rui Yuan, Xien Gui, Hengning Ke, Ke Zhuang, Hui Hu, Ling Li, Ling Feng, Xingxia Yu, Yajun Yan, Mingqi Luo

JMIR Public Health Surveill 2024;10:e46750

Hepatitis C Knowledge and Self-Reported Testing Behavior in the General Population in China: Online Cross-Sectional Survey

Hepatitis C Knowledge and Self-Reported Testing Behavior in the General Population in China: Online Cross-Sectional Survey

However, there is a lack of information about HCV testing behavior and willingness to undergo HCV screening in the general Chinese population. This study was conducted to assess HCV knowledge, self-reported HCV testing behavior, and willingness to undergo HCV screening in the general Chinese population to inform policy decision-making aimed at eliminating HCV. The characteristics of patients who have less knowledge and are less likely to undergo testing were also explored.

Yin Liu, Juan Su, Xiaoyang Wang, Huifang Xu, Hong Wang, Ruihua Kang, Liyang Zheng, Yixian Wang, Chunya Liu, Yiping Jing, Shaokai Zhang

JMIR Public Health Surveill 2023;9:e39472

Testing for Hepatitis C During Pregnancy Among Persons With Medicaid and Commercial Insurance: Cohort Study

Testing for Hepatitis C During Pregnancy Among Persons With Medicaid and Commercial Insurance: Cohort Study

HCV can be transmitted during pregnancy or delivery—an estimated 5.8% of infants born to women with HCV infection become infected [4]. Perinatal infection can result in liver disease during adulthood and sequelae such as cirrhosis and hepatocellular carcinoma [5]. The incidence of acute HCV infection in the United States increased annually from 2009 to 2019, with rates highest among adults 20-29 and 30-39 years of age, including women of childbearing age [6,7].

Mohammed A Khan, William W Thompson, Ademola Osinubi, William A Meyer 3rd, Harvey W Kaufman, Paige A Armstrong, Monique A Foster, Noele P Nelson, Carolyn Wester

JMIR Public Health Surveill 2023;9:e40783

Coproduction of Low-Barrier Hepatitis C Virus and HIV Care for People Who Use Drugs in a Rural Community: Brief Qualitative Report

Coproduction of Low-Barrier Hepatitis C Virus and HIV Care for People Who Use Drugs in a Rural Community: Brief Qualitative Report

Infections such as hepatitis C (HCV) and HIV disproportionally affect people who inject drugs. Globally, over half of people who inject drugs are infected with HCV, and nearly 1 in 5 with HIV [1-5]. Many people who inject drugs are unaware of their HCV or HIV status, and rates of accessing treatment are low. For instance, fewer than 10% of those infected with HCV receive treatment [6], increasing morbidity and contributing to ongoing virus spread [7].

Shoshana H Bardach, Amanda N Perry, Elizabeth Eccles, Elizabeth A Carpenter-Song, Ryan Fowler, Erin M Miers, Anais Ovalle, David de Gijsel

J Particip Med 2023;15:e47395

A Video-Observed Treatment Strategy to Improve Adherence to Treatment Among Persons Who Inject Drugs Infected With Hepatitis C Virus: Qualitative Study of Stakeholder Perceptions and Experiences

A Video-Observed Treatment Strategy to Improve Adherence to Treatment Among Persons Who Inject Drugs Infected With Hepatitis C Virus: Qualitative Study of Stakeholder Perceptions and Experiences

Hepatitis C virus (HCV) is highly prevalent among people who inject drugs [1-5]. The advent of direct-acting antivirals has the potential to halt the HCV epidemic and dramatically reduce the public health burden of the disease. Yet, despite the availability of these new highly efficacious regimens, HCV treatment uptake in this group has been limited by barriers at the individual, health system, social, and economic levels [1,6-8].

Alison Karasz, Krupa Merchant, Julia Arnsten, Judith Feinberg, Arthur Y Kim, Paula J Lum, Melissa Diane McKee, Shruti H Mehta, Paul Meissner, Brianna L Norton, Kimberly Page, Irene Pericot-Valverde, Reena Singh, Ellen Stein, Lynn E Taylor, Judith I Tsui, Katherine Wagner, Alain Litwin

J Med Internet Res 2023;25:e38176

Design and Implementation of a Multilevel Intervention to Reduce Hepatitis C Transmission Among Men Who Have Sex With Men in Amsterdam: Co-Creation and Usability Study

Design and Implementation of a Multilevel Intervention to Reduce Hepatitis C Transmission Among Men Who Have Sex With Men in Amsterdam: Co-Creation and Usability Study

Hepatitis C virus (HCV) infection is a major public health problem: An estimated 71 million people worldwide are living with chronic HCV infection, which, if left untreated, may progress to serious liver disease [1]. In 2016, approximately 399,000 people died from HCV-related cirrhosis and liver cancer, and the number of deaths increases each year [2].

Tamara Prinsenberg, Paul Zantkuijl, Wim Zuilhof, Udi Davidovich, Janke Schinkel, Maria Prins, Marc van der Valk

JMIR Form Res 2020;4(9):e19100

Wirelessly Observed Therapy to Optimize Adherence and Target Interventions for Oral Hepatitis C Treatment: Observational Pilot Study

Wirelessly Observed Therapy to Optimize Adherence and Target Interventions for Oral Hepatitis C Treatment: Observational Pilot Study

The World Health Organization estimated that in 2015, 71 million people worldwide were living with chronic hepatitis C virus (HCV) infection. Although recent studies report that the incidence of HCV has decreased during the past 50 years [1-3], estimates obtained from modeling suggest that in 2015, there were still 1.75 million new HCV infections worldwide—a global incidence rate of 23.7 per 100,000 [4].

Maurizio G Bonacini, Yoona Kim, Caroline Pitney, Lee McKoin, Melody Tran, Charles Landis

J Med Internet Res 2020;22(4):e15532