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Microfragmented Fat and Biphasic Calcium Phosphates for Alveolar Cleft Repair: Protocol for a Prospective, Nonblinded, First-in-Human Clinical Study

Microfragmented Fat and Biphasic Calcium Phosphates for Alveolar Cleft Repair: Protocol for a Prospective, Nonblinded, First-in-Human Clinical Study

Alveolar cleft is defined as a bone gap in the primary palate from the nasal sill to the incisive foramen [1]. The defect occurs as a result of disruption of primary palate development between 4 and 12 weeks of gestational age, specifically in the frontonasal prominence [2]. The treatment protocol varies on the basis of the following factors: timing, surgical procedure, and grafting material.

Diandra Sabrina Natsir Kalla, Salem Alkaabi, Abul Fauzi, Andi Tajrin, Rifaat Nurrahma, Werner E G Müller, Heinz C Schröder, Xiaohong Wang, Tymour Forouzanfar, Marco N Helder, Muhammad Ruslin

JMIR Res Protoc 2024;13:e42371