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Developing and Validating a Self-Care Self-Efficacy Scale for Oral Anticoagulation Therapy in Patients With Nonvalvular Atrial Fibrillation: Protocol for a Mixed Methods Study

Developing and Validating a Self-Care Self-Efficacy Scale for Oral Anticoagulation Therapy in Patients With Nonvalvular Atrial Fibrillation: Protocol for a Mixed Methods Study

Oral anticoagulation therapy (OAC) represents the primary and secondary prevention choice for venous thromboembolism and stroke in patients with nonvalvular atrial fibrillation (NVAF) [1]. As a life-long treatment, OAC is prescribed for various clinical indications, such as heart failure, congenital heart disease, hematological disorders, and peripheral vascular disease, affecting approximately 2% of the Western population.

Arianna Magon, Jeroen Hendriks, Rosario Caruso

JMIR Res Protoc 2024;13:e51489

Evaluation of Machine Learning Approaches for Predicting Warfarin Discharge Dose in Cardiac Surgery Patients: Retrospective Algorithm Development and Validation Study

Evaluation of Machine Learning Approaches for Predicting Warfarin Discharge Dose in Cardiac Surgery Patients: Retrospective Algorithm Development and Validation Study

Because the intensity of postsurgical anticoagulation required for a given patient is determined by the nature of cardiac surgery performed, we developed and validated separate models for predicting the warfarin dose required for achieving a discharge INR of 2.0-3.0 in patients undergoing all forms of cardiac surgery other than mechanical mitral valve replacement (ie, prosthetic tissue valve replacement, postsurgical atrial fibrillation, and mechanical aortic valve replacement) and a discharge INR of 2.5-3.5

Lindsay Dryden, Jacquelin Song, Teresa J Valenzano, Zhen Yang, Meggie Debnath, Rebecca Lin, Jane Topolovec-Vranic, Muhammad Mamdani, Tony Antoniou

JMIR Cardio 2023;7:e47262

Smartphone Apps for Managing Antithrombotic Therapy: Scoping Literature Review

Smartphone Apps for Managing Antithrombotic Therapy: Scoping Literature Review

Antithrombotic therapy, including both anticoagulation and platelet aggregation inhibition, is a common therapy for the treatment and prevention of atrial fibrillation (AFib)–related thromboembolic events [1], venous thromboembolism [2], and coronary artery disease [3]. European guidelines recommend oral anticoagulation (OAC) for most patients with AFib and platelet aggregation inhibitors for every patient diagnosed with coronary artery disease without contraindications [3,4].

Friederike Praus, Bartosz Krzowski, Tabea Walther, Christian Gratzke, Paweł Balsam, Arkadiusz Miernik, Philippe Fabian Pohlmann

JMIR Cardio 2022;6(1):e29481

Usability and Perceived Usefulness of the AFib 2gether Mobile App in a Clinical Setting: Single-Arm Intervention Study

Usability and Perceived Usefulness of the AFib 2gether Mobile App in a Clinical Setting: Single-Arm Intervention Study

As AF is a major risk factor for stroke, professional societies recommend anticoagulation (AC) in most patients; however, some patients are reluctant to start taking it. Limited health literacy, inaccurate perception of the risk of AF, and lack of trust in physicians contribute to patient refusal, with up to 39.3% (257,415/655,000) of patients remaining off AC across the country [6-8]. Among the patients who start AC, many discontinue treatment, especially after the onset of bleeding or other setbacks.

Alok Kapoor, Anna Hayes, Jay Patel, Harshal Patel, Andreza Andrade, Kathleen Mazor, Carl Possidente, Kimberly Nolen, Rozelle Hegeman-Dingle, David McManus

JMIR Cardio 2021;5(2):e27016

Online Search Trends Influencing Anticoagulation in Patients With COVID-19: Observational Study

Online Search Trends Influencing Anticoagulation in Patients With COVID-19: Observational Study

The appropriate prescribing of thromboprophylaxis or anticoagulation therapy within 24 hours of admission or 24 hours of a positive COVID-19 result were collected. Three local interventions in the hospital were noted as key events that influenced anticoagulation and thromboprophylaxis guidelines for patients with COVID-19.

Amy P Worrall, Claire Kelly, Aine O'Neill, Murray O'Doherty, Eoin Kelleher, Anne Marie Cushen, Cora McNally, Samuel McConkey, Siobhan Glavey, Michelle Lavin, Eoghan de Barra

JMIR Form Res 2021;5(8):e21817

A Patient Decision Aid for Anticoagulation Therapy in Patients With Nonvalvular Atrial Fibrillation: Development and Pilot Study

A Patient Decision Aid for Anticoagulation Therapy in Patients With Nonvalvular Atrial Fibrillation: Development and Pilot Study

The latest cardiovascular clinical guidelines already recommend the use of SDM to facilitate an individualized approach to anticoagulation therapy in patients with nonvalvular AF [13]. While the benefits of using PDAs have been validated in Western countries, SDM still remains a novel concept in Asia where paternalism is still the norm [14]. Nevertheless, it has been found that patients in Asia want to be involved in SDM [15,16].

Kim Paul de Castro, Harold Henrison Chiu, Ronna Cheska De Leon-Yao, Lorraine Almelor-Sembrana, Antonio Miguel Dans

JMIR Cardio 2021;5(2):e23464

Effectiveness of the Alfalfa App in Warfarin Therapy Management for Patients Undergoing Venous Thrombosis Prevention and Treatment: Cohort Study

Effectiveness of the Alfalfa App in Warfarin Therapy Management for Patients Undergoing Venous Thrombosis Prevention and Treatment: Cohort Study

Alfalfa consists of a background management system and a remote anticoagulation management system. This remote anticoagulation management system can be divided into a patient terminal called Alfalfa Health Management and a medical terminal called Alfalfa Anticoagulation Guidance.

Hua Cao, Shaojun Jiang, Meina Lv, Tingting Wu, Wenjun Chen, Jinhua Zhang

JMIR Mhealth Uhealth 2021;9(3):e23332

Usability, Perceived Usefulness, and Shared Decision-Making Features of the AFib 2gether Mobile App: Protocol for a Single-Arm Intervention Study

Usability, Perceived Usefulness, and Shared Decision-Making Features of the AFib 2gether Mobile App: Protocol for a Single-Arm Intervention Study

Anticoagulation (AC) is the mainstay of therapy, but many patients are reluctant to start taking anticoagulants [6]. Patients who have a diagnosis of AF generally have a higher risk of stroke than the general population [7]. Even among those who do start AC therapy, many do not persist with the treatment after bleeding or other setbacks. Providers also struggle with balancing the risks and benefits of AC therapy.

Alok Kapoor, Andreza Andrade, Anna Hayes, Kathleen Mazor, Carl Possidente, Kim Nolen, Rozelle Hegeman-Dingle, David McManus

JMIR Res Protoc 2021;10(2):e21986