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A few more details about the adverse outcomes of the 3 children with multiple inflammatory syndrome in children (MIS-C) would be appreciated by the reader. Were there any relevant circumstances or peculiarities for these cases?
5. References 7 and 8 might be wrong, as they do not relate to infections in children, as mentioned in the article. More appropriate references could be sought.
6.
JMIRx Med 2024;5:e60168
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A few more details about the adverse outcomes of the 3 children with multiple inflammatory syndrome in children (MIS-C) would be appreciated by the reader. Were there any relevant circumstances or peculiarities for these cases?
Response: We agree that providing more details on the adverse outcomes of the MIS-C cases would enhance the comprehensibility of our findings.
JMIRx Med 2024;5:e59327
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Subsequently, multisystem inflammatory syndrome in children (MIS-C) was first observed in children and adolescents in the United Kingdom in April 2020, raising alarms about their safety, particularly in the absence of vaccines approved for children [4,5]. This was soon followed by detailed reports and linkage of MIS-C to SARS-Co V-2 [6]. The initial phase of pandemic caused numerous infections among children in India but no serious illness [7].
JMIRx Med 2024;5:e48629
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Inflammatory bowel disease (IBD), encompassing Crohn disease and ulcerative colitis, is characterized by chronic digestive tract inflammation. This condition leads to a range of symptoms that significantly impact the quality of life [18]. The persistent symptoms and activity of IBD, even with the best medical or surgical interventions, highlight the critical need for ongoing surveillance and management [19].
J Med Internet Res 2024;26:e58497
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From the Cochrane Library: Leukotriene Receptor Antagonists for Eczema
Atopic dermatitis (AD), a chronic inflammatory skin disease, is estimated to affect up to 10% of adults and 20% of children worldwide [1]. Clinical manifestations include pruritus, skin lesions, and dry scaly skin [2,3]. First-line treatment includes topical steroids and emollients, with systemic steroids or immune modulators for moderate-to-severe AD.
JMIR Dermatol 2024;7:e50434
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Arabic Web-Based Information on Oral Lichen Planus: Content Analysis
Oral lichen planus (OLP) is a prevalent chronic inflammatory mucocutaneous disease that frequently affects the oral mucosa. Between 0.5%-2% of the world’s population is affected by OLP [17-19]. In a review of studies conducted in Arab countries, OLP had a potential malignant transformation rate ranging from 0.4% to 6.5% [20].
JMIR Form Res 2024;8:e49198
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Psoriasis is a chronic inflammatory skin condition characterized by red, itchy, scaly patches that affects approximately 2% of the global population and has a significant effect on the patient’s quality of life [1]. Exploring epidemiological trends and relevant risk factors for psoriasis is vital to effectively reduce the global burden of the disease by directing efforts toward countries with the highest prevalence.
JMIR Dermatol 2024;7:e48749
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Exploring the Perspectives of Patients Living With Lupus: Retrospective Social Listening Study
Systemic lupus erythematosus (SLE) is an autoimmune inflammatory disease affecting multiple systems in the body; it is characterized by fluctuating symptoms and periods of exacerbation and remission [1-3]. The most common symptoms of SLE include fatigue, skin rashes, fever, and joint pain or swelling [3]. SLE has several phenotypes and clinical manifestations involving various organs, including the joints, skin, kidneys, and organs of the neurological or hematological systems [1,2].
JMIR Form Res 2024;8:e52768
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Hyaluronidase for Dermal Filler Complications: Review of Applications and Dosage Recommendations
It is generally believed that permanent fillers are nonbiodegradable and nonreversible, and therefore, complications with the inflammatory process are more likely to occur with permanent fillers. Dermal fillers have gained popularity over the past 2 decades despite the large spectrum of complications associated with their use, including nodule formation, misplacement, migration, infection, and vascular occlusion [1-3].
JMIR Dermatol 2024;7:e50403
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