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Patient and Provider Perspectives of a Web-Based Intervention to Support Symptom Management After Radioactive Iodine Treatment for Differentiated Thyroid Cancer: Qualitative Study

Patient and Provider Perspectives of a Web-Based Intervention to Support Symptom Management After Radioactive Iodine Treatment for Differentiated Thyroid Cancer: Qualitative Study

Differentiated thyroid cancer (DTC) is the most common endocrine malignancy among the estimated 44,020 new cases of thyroid cancer in the United States annually [4]. DTC involves a spectrum of disease presentations characterized by different levels of risk of recurrence. For patients with a high risk of recurrence, the standard of care involves total thyroidectomy followed by radioactive iodine (RAI) treatment and thyroid hormone therapy [5-7].

Alaina L Carr, Angela M Jenkins, Jacqueline Jonklaas, Kate Gabriel, Kristen E Miller, Kristi D Graves

JMIR Form Res 2025;9:e60588

Current Status and Future Directions of Ferroptosis Research in Breast Cancer: Bibliometric Analysis

Current Status and Future Directions of Ferroptosis Research in Breast Cancer: Bibliometric Analysis

Despite the considerable progress achieved through sustained research in breast cancer diagnosis, treatment, and prevention, the intricate etiology of this malignancy remains widely undeciphered. Consequently, there is an urgent need to delve deeper into the complex mechanisms that underlie its development, with the aim of developing more precise and efficacious strategies for its management [3].

Jia-Yuan Luo, Yu-Long Deng, Shang-Yi Lu, Si-Yan Chen, Rong-Quan He, Di-Yuan Qin, Bang-Teng Chi, Gang Chen, Xia Yang, Wei Peng

Interact J Med Res 2025;14:e66286

Interpretable Machine Learning to Predict the Malignancy Risk of Follicular Thyroid Neoplasms in Extremely Unbalanced Data: Retrospective Cohort Study and Literature Review

Interpretable Machine Learning to Predict the Malignancy Risk of Follicular Thyroid Neoplasms in Extremely Unbalanced Data: Retrospective Cohort Study and Literature Review

Specifically, we aimed to individualize the clinical decision-making for patients with FTN by using interpretable machine learning to not only predict the malignancy risk of FTN but also identify the important predictors that might contribute to the prediction. This retrospective cohort study followed the suggestions of the TRIPOD (Transparent Reporting of a Multivariable Prediction Model for Individual Prognosis or Diagnosis) statement [23]. Figure 1 shows the framework of our study.

Rui Shan, Xin Li, Jing Chen, Zheng Chen, Yuan-Jia Cheng, Bo Han, Run-Ze Hu, Jiu-Ping Huang, Gui-Lan Kong, Hui Liu, Fang Mei, Shi-Bing Song, Bang-Kai Sun, Hui Tian, Yang Wang, Wu-Cai Xiao, Xiang-Yun Yao, Jing-Ming Ye, Bo Yu, Chun-Hui Yuan, Fan Zhang, Zheng Liu

JMIR Cancer 2025;11:e66269

Public Health Risks, Dermatological Manifestations, and Environmental Justice Associated With Vinyl Chloride Exposure: Narrative Review

Public Health Risks, Dermatological Manifestations, and Environmental Justice Associated With Vinyl Chloride Exposure: Narrative Review

Not surprisingly, the heavily industrialized corridor between New Orleans and Baton Rouge is known as “cancer alley” because of the region’s markedly higher rates of malignancy [18]. Under the Toxics Release Inventory (TRI) Program, the Environmental Protection Agency (EPA) tracks toxic chemicals that pose a threat to human health and the environment, including VC [2,19].

Rachel S Goodman, Lavanya Mittal, Eva Rawlings Parker

JMIR Dermatol 2023;6:e48998

Mapping the Evidence for Opioid-Mediated Changes in Malignancy and Chemotherapeutic Efficacy: Protocol for a Scoping Review

Mapping the Evidence for Opioid-Mediated Changes in Malignancy and Chemotherapeutic Efficacy: Protocol for a Scoping Review

At present, there is no consensus on the risk or benefit posed by opioids in the context of malignancy and its treatment. While multiple clinical studies have been conducted to evaluate the relationship between malignancy and its treatment with the µOR and analgesic opioid use, interpreting the risks or benefits of opioid use on tumor growth remains challenging and often confusing. Public response to some literature reports has led to surges in demand for opioids as potential antineoplastics.

Jonathan E Constance, Mary M McFarland, Tallie Casucci, Michael W Deininger, Elena Y Enioutina, Kathleen Job, Richard S Lemons, Carol S Lim, Robert M Ward, Venkata Yellepeddi, Kevin M Watt

JMIR Res Protoc 2023;12:e38167

Exploring Urological Malignancies on Pinterest: Content Analysis

Exploring Urological Malignancies on Pinterest: Content Analysis

Highest repins for each urological malignancy. The overall quality of pins was low. Nearly three-fourths of the pins contained moderate- to poor-quality information, or a DISCERN ≤3. Poor-quality pins do not state its purpose, have relevant content, identify sources of information, address quality of life, risks of treatment, or other available treatment options. Nearly all pins failed to mention shared decision-making (n=348, 97%).

Amber S Herbert, Naeemul Hassan, Rena D Malik, Stacy Loeb, Akya Myrie

JMIR Cancer 2022;8(3):e36244

A Review of Artificial Intelligence Applications in Hematology Management: Current Practices and Future Prospects

A Review of Artificial Intelligence Applications in Hematology Management: Current Practices and Future Prospects

The “Results” section discusses and classifies existing research based on malignancy type and stage, respectively. Finally, the “Discussion” section provides a detailed analysis of AI applications for hematologic malignancies. In this review, peer-reviewed and publicly available journal papers were identified from a variety of online databases, while publicly unavailable copies were obtained through our institutional access to journal publications and databases.

Yousra El Alaoui, Adel Elomri, Marwa Qaraqe, Regina Padmanabhan, Ruba Yasin Taha, Halima El Omri, Abdelfatteh EL Omri, Omar Aboumarzouk

J Med Internet Res 2022;24(7):e36490