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Seasonal Malaria Chemoprevention Therapy in Children Up To 9 Years of Age: Protocol for a Cluster-Randomized Trial Study

Seasonal Malaria Chemoprevention Therapy in Children Up To 9 Years of Age: Protocol for a Cluster-Randomized Trial Study

These efforts have been carried out through increased preventive and treatment measures such as long-lasting insecticide-treated mosquito nets (LLINs), indoor residual spraying, artemisinin-based combination therapies (ACTs), and intermittent preventive treatment of pregnant women (IPTp); and more recently, seasonal malaria chemoprevention (SMC). The most widely implemented malaria control interventions are the joint use of LLINs and rapid treatment of malaria cases with ACTs, IPTp, and SMC.

Mahamoudou Toure, Jeffrey G Shaffer, Daouda Sanogo, Soumba Keita, Moussa Keita, Fousseyni Kane, Bourama Traore, Djeneba Dabitao, Aissata Kone, Cheick Oumar Doumbia, Joseph Keating, Joshua Yukich, Helle H Hansson, Alyssa E Barry, Mahamadou Diakité, Michael Alifrangis, Seydou Doumbia

JMIR Res Protoc 2024;13:e51660

Repeat Ivermectin Mass Drug Administrations for Malaria Control II: Protocol for a Double-blind, Cluster-Randomized, Placebo-Controlled Trial for the Integrated Control of Malaria

Repeat Ivermectin Mass Drug Administrations for Malaria Control II: Protocol for a Double-blind, Cluster-Randomized, Placebo-Controlled Trial for the Integrated Control of Malaria

Given the major contribution of vector control interventions to malaria control, it is not surprising that widespread mosquito resistance to the insecticide classes being used in ITNs and IRS (including pyrethroids, carbamates, and organophosphates) and behavioral avoidance (biting outdoors, resting outdoors, or biting at times when individuals are not sleeping under ITNs) are principal reasons for this stagnation in gains.

Brian D Foy, Anthony Some, Tereza Magalhaes, Lyndsey Gray, Sangeeta Rao, Emmanuel Sougue, Conner L Jackson, John Kittelson, Hannah C Slater, Teun Bousema, Ollo Da, A Gafar V Coulidiaty, McKenzie Colt, Martina Wade, Kacey Richards, A Fabrice Some, Roch K Dabire, Sunil Parikh

JMIR Res Protoc 2023;12:e41197