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This paper presents a transcriptomic study protocol for examining host and pathogen interactions using a data-driven approach with unsupervised analysis. Our hypotheses are that genetic diversity accounts for the variation in outcomes that follow interactions between humans and the potentially life-threatening pathogens in NSTIs and that these interactions are modulated by HBO2 treatment.
This is a prospective observational study.
JMIR Res Protoc 2022;11(11):e39252
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