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Effect of Multimodal App-Based Interventions on Glycemic Control in Patients With Type 2 Diabetes: Systematic Review and Meta-Analysis

Effect of Multimodal App-Based Interventions on Glycemic Control in Patients With Type 2 Diabetes: Systematic Review and Meta-Analysis

Hemoglobin A1c (Hb A1c; long-term blood glucose) levels were also significantly reduced with 56.1% of participants achieving a Hb A1c value of Blood glucose control is a key target for such interventions, to lower cardiovascular risk as well as mortality from T2 DM [5]. In adults with T2 DM, the Hb A1c target value is set individually, depending on various factors, such as diabetes duration, comorbidities, and patient preference, but it lies within the corridor of 6.5%-8.5% [10].

Emma Bodner, Lena Roth, Kathleen Wiencke, Christian Bischoff, Peter EH Schwarz

J Med Internet Res 2025;27:e54324

Improving Self-Efficacy, Quality of Life, and Glycemic Control in Adolescents With Type 1 Diabetes: Randomized Controlled Trial for the Evaluation of the Family-Centered Empowerment Model

Improving Self-Efficacy, Quality of Life, and Glycemic Control in Adolescents With Type 1 Diabetes: Randomized Controlled Trial for the Evaluation of the Family-Centered Empowerment Model

One possibility of results of this type of study indicates that the use of family-focused models in diabetes treatment may not only improve clinical measures, including glycosylated hemoglobin (Hb A1c), but also dramatically influence psychosocial health. Family-centered interventions are medical strategies that involve family members in the management and treatment of a patient’s disease.

Salah Alzawahreh, Candan Ozturk

JMIR Form Res 2024;8:e64463

Whole-Body Cryotherapy Reduces Systemic Inflammation in Healthy Adults: Pilot Cohort Study

Whole-Body Cryotherapy Reduces Systemic Inflammation in Healthy Adults: Pilot Cohort Study

Blood biomarkers measured include serum high-sensitivity C-reactive protein (hs CRP), fasting glucose, hemoglobin A1c (Hb A1c), low-density lipoprotein (LDL) and high-density lipoprotein (HDL), and triglycerides. All blood was drawn from the median cubital vein with a 20-gauge intravenous catheter needle.

Elizabeth Chun, Richard Joseph, Rachele Pojednic

Interact J Med Res 2024;13:e60942

Efficacy of Save Medical Corporation (SMC)–01, a Smartphone App Designed to Support Type 2 Diabetes Self-Management Based on Established Guidelines: Randomized Controlled Trial

Efficacy of Save Medical Corporation (SMC)–01, a Smartphone App Designed to Support Type 2 Diabetes Self-Management Based on Established Guidelines: Randomized Controlled Trial

We set the mean difference in the change in Hb A1c from the baseline that we were designing the study to detect to 0.5, as this is generally considered a clinically significant change in Hb A1c [26,27]. The SD common to both groups was set to 1 based on values from previous studies [23,28,29], and the 2-sided significance level was 5% with 90% power. The resulting required sample size is 86 for each group.

Nicholas Leung, Kayo Waki, Satoshi Nozoe, Shunpei Enomoto, Ryo Saito, Sakurako Hamagami, Toshimasa Yamauchi, Masaomi Nangaku, Kazuhiko Ohe, Yukiko Onishi

J Med Internet Res 2024;26:e53740

Outcomes of an Asynchronous Care Model for Chronic Conditions in a Diverse Population: 12-Month Retrospective Chart Review Study

Outcomes of an Asynchronous Care Model for Chronic Conditions in a Diverse Population: 12-Month Retrospective Chart Review Study

The first and last available Hb A1c results were compared among all included members, as well as in the subgroups with a baseline Hb A1c >8% (poor control group) and a baseline Hb A1c >9% (uncontrolled hyperglycemia group) using paired 2-tailed t tests.

Michael Hofner, Patrick Hurnaus, Dan DiStefano, Shaji Philip, Sarah Kim, Julie Shaw, Avantika Chander Waring

JMIR Diabetes 2024;9:e53835

Examining a Remote Group-Based Type 2 Diabetes Self-Management Education Program in the COVID-19 Era Using the ORBIT Model: Small 6-Week Feasibility Study

Examining a Remote Group-Based Type 2 Diabetes Self-Management Education Program in the COVID-19 Era Using the ORBIT Model: Small 6-Week Feasibility Study

To examine the potential impact of the program on behavioral and clinical risk factors, device-assessed (4) weekly mean daily step count and (5) estimated glycated hemoglobin (Hb A1c; the average glucose level from the Free Style Libre readings for 14 or more days [17]) were collected. Given the small, single cohort and preparatory nature of this ORBIT phase 1b feasibility study, individual and group-level data are presented descriptively rather than with inferential statistics.

Madison S Hiemstra, Sonja M Reichert, Marc S Mitchell

JMIR Form Res 2024;8:e46418

The Effect of Mobile eHealth Education to Improve Knowledge, Skills, Self-Care, and Mobile eHealth Literacies Among Patients With Diabetes: Development and Evaluation Study

The Effect of Mobile eHealth Education to Improve Knowledge, Skills, Self-Care, and Mobile eHealth Literacies Among Patients With Diabetes: Development and Evaluation Study

Hb A1c serves as a crucial indicator of glycemic control, reflecting the average blood glucose level over 3 months. The Hb A1c data for the study participants were obtained by reviewing electronic medical records during the enrollment period. Hb A1c of 7% serves as a cutoff point and a value less than 7% is considered indicative of good control. Higher levels of Hb A1c suggest poor glycemic control, which is associated with an elevated risk of vascular complications and death [39,50].

Sophie Huey-Ming Guo, Jiun-Lu Lin, Hung-Chun Hsing, Chun-Chuan Lee, Shih-Ming Chuang

J Med Internet Res 2023;25:e42497

Family-Based, Culturally Responsive Intervention for Chinese Americans With Diabetes: Lessons Learned From a Literature Review to Inform Study Design and Implementation

Family-Based, Culturally Responsive Intervention for Chinese Americans With Diabetes: Lessons Learned From a Literature Review to Inform Study Design and Implementation

Mc Ewen et al [9] reported significant improvement of diabetes management outcomes, such as diabetes management activities, but not of Hb A1c. Cai and Hu [11] conducted a 2-group quasiexperimental study (without randomization of participants): 29 dyads in the intervention group and 28 dyads in the control group. Hu et al [12] conducted a 2-group quasiexperimental study (92 dyads): 51 dyads in the intervention group and 41 dyads in the control group. Both studies showed a significant reduction in Hb A1c.

Wen-Wen Li, Jacqueline Tong

Asian Pac Isl Nurs J 2023;7:e48746