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Reference 24: A critical review of large language models: sensitivity, bias, and the path toward specialized
JMIR AI 2025;4:e64447
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The Role of AI in Nursing Education and Practice: Umbrella Review
Reference 23: PICO, PICOS and SPIDER: a comparison study of specificity and sensitivity in three search
J Med Internet Res 2025;27:e69881
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For the 3 novel instruments, we conducted a validation study collecting validity evidence from 4 of 5 potential sources [39,40]: content (ie, grounding of the instruments in theory and prior empirical work); internal structure (ie, rating reproducibility); relations with other variables (ie, sensitivity of ratings to case differences, including expectation of higher ratings for more advanced LLM models and human clinician personas); and response process (ie, clarification on why raters responded as they did)
J Med Internet Res 2025;27:e68486
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To verify the robustness of the findings, we performed sensitivity analyses to test the effects of underlying database choices in the LCA model. Monte Carlo simulations of 1000 runs served as an uncertainty analysis for the investigated reference scenarios, using reported ranges of collected data and pedigree matrix-computed ranges of background data [24].
J Med Internet Res 2025;27:e67538
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Molecular approaches such as real-time polymerase chain reaction offer increased sensitivity and efficiency and require only 1 sample for testing. Immunodiagnostic approaches targeting parasite antigens or host antibodies improve sensitivity and specificity. Despite advances, there is no one-size-fits-all strategy for diagnosis, which requires careful evaluation of aspects such as the suspected parasite, the nature of the sample, and the resources available [8].
JMIR Res Protoc 2025;14:e66350
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Results indicated that 282 participants after attrition would be needed for 80% power (P
With regard to power for moderation analyses, we ran a sensitivity analysis to compute the smallest effect size our study would be powered to find using 280 given 4 groups (eg, 2 study arms × 2 genders). With N=280, G*Power calculations [63] show our study would have a 95% chance (with P
Patients will complete surveys at baseline, 6, 12, and 18 months.
JMIR Res Protoc 2025;14:e64449
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To corroborate the findings, a sensitivity analysis was run, which used the median as the test statistic difference (instead of the mean difference) of the permutation test.
In a separate analysis, smartphones were compared against tablets to evaluate the impact of screen size on measurement equivalence. Differences between smartphones and tablets were assessed for statistical significance with the Mann-Whitney U Test.
Smartphone data were available for 2010 participants aged 18 years and older.
J Med Internet Res 2025;27:e63090
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In our validation study, PMIS was shown to have high validity for distinguishing older adults with cognitive impairment from those without, regardless of age, sex, education, or presence of depression (sensitivity and specificity >90%) as well as excellent reliability (intraclass correlation 0.91) [37,38].
The second item in the 5-Cog battery is the Symbol Match [39], developed by one of our coinvestigators (EFW).
JMIR Res Protoc 2025;14:e60471
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As such, the cultural sensitivity of treatments should be considered as a dynamic condition related to time and context [53].
JMIR Form Res 2025;9:e65412
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Reference 13: Anxiety sensitivity and intolerance of uncertainty as potential risk factors for cyberchondria Reference 33: Anxiety sensitivity and intolerance of uncertainty: transdiagnostic risk factors for anxiety
J Med Internet Res 2025;27:e72414
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